Evidence map›Paper›PMID 29854968›Full record

ArticleKidney international reports2018

Impact of CKD on Household Income.

Rachael L Morton, Iryna Schlackow, Alastair Gray, Jonathan Emberson, William Herrington, Natalie Staplin, Christina Reith, Kirsten Howard, Martin J Landray, Alan Cass and 3 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Syndemic analysis of stroke in Indonesia.The Lancet regional health. Western Pacific · 2026
    Article
  3. Review
  4. Observational
  5. Inequities in kidney health and kidney care.Nature reviews. Nephrology · 2023
    Review
  6. Article
  7. O-GlcNAcylation in Renal (Patho)Physiology.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Social Determinants of CKD Hotspots.Seminars in nephrology · 2019
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Rachael L MortonNHMRC Clinical Trials Centre, The University of Sydney, Sydney, Australia.
Iryna SchlackowHealth Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK.
Alastair GrayHealth Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK.
Jonathan EmbersonClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
William HerringtonClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
Natalie StaplinClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
Christina ReithClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
Kirsten HowardSchool of Public Health, The University of Sydney, Sydney, Australia.
Martin J LandrayClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
Alan CassMenzies School of Health Research, Charles Darwin University, Darwin, Australia.
Colin BaigentClinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, UK.
Borislava MihaylovaHealth Economics Research Centre, Nuffield Department of Population Health, University of Oxford, UK.
SHARP Collaborative Group
University of Oxford · GBThe University of Sydney · AUCharles Darwin University · AU

Funding

Medical Research Council MC_U137686853Medical Research Council MC_UU_12026/3Medical Research Council MC_UU_12026/5Medical Research Council MR/R007764/1
6 · The paper itself

Abstract

introductionThe impact of chronic kidney disease (CKD) on income is unclear. We sought to determine whether CKD severity, serious adverse events, and CKD progression affected household income.

methodsAnalyses were undertaken in a prospective cohort of adults with moderate-to-severe CKD in the Study of Heart and Renal Protection (SHARP), with household income information available at baseline screening and study end. Logistic regressions, adjusted for sociodemographic characteristics, smoking, and prior diseases at baseline, estimated associations during the 5-year follow-up, among (i) baseline CKD severity, (ii) incident nonfatal serious adverse events (vascular or cancer), and (iii) CKD treatment modality (predialysis, dialysis, or transplanted) at study end and the outcome "fall into relative poverty." This was defined as household income <50% of country median income.

resultsA total of 2914 SHARP participants from 14 countries were included in the main analysis. Of these, 933 (32%) were in relative poverty at screening; of the remaining 1981, 436 (22%) fell into relative poverty by study end. Compared with participants with stage 3 CKD at baseline, the odds of falling into poverty were 51% higher for those with stage 4 (odds ratio [OR]: 1.51; 95% confidence interval [CI]: 1.09-2.10), 66% higher for those with stage 5 (OR: 1.66; 95% CI: 1.11-2.47), and 78% higher for those on dialysis at baseline (OR: 1.78, 95% CI: 1.22-2.60). Participants with kidney transplant at study end had approximately half the risk of those on dialysis or those with CKD stages 3 to 5.

conclusionMore advanced CKD is associated with increased odds of falling into poverty. Kidney transplantation may have a role in reducing this risk.

Indexed as

chronic renal insufficiencydialysisincomepovertytransplantation

Identifiers

PMID29854968
PMCPMC5976816
OpenAlexW2779570140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.