Evidence map›Paper›PMID 29854884›Full record

ArticleJournal of dentistry (Shiraz, Iran)2018

Arg753gln and Arg677 Trp Polymorphisms of Toll-Like Receptor 2 In Acute Apical Abscess.

Ebrahim Miri-Moghaddam, Narges Farhad Mollashahi, Nava Naghibi, Yasaman Garme, Ali Bazi

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of dentistry (Shiraz, Iran), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ebrahim Miri-MoghaddamCellular & Molecular Research Center & Dept. of Molecular Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Narges Farhad MollashahiOral and Dental Diseases Research Center, Dept. of Endodontics, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Nava NaghibiFaculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran.
Yasaman GarmeCellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Ali BaziFaculty of Allied Medical Sciences, Zabol University of Medical Sciences, Zabol, Iran.
Zahedan University of Medical Sciences · IRZabol University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

statement of the problemGenetic polymorphisms can alter immunity response against pathogens, which in turn influence individuals' susceptibility to certain infections. PURPOSE: Our aim was to determine the association of Arg753Gln (rs5743708) and Arg677Trp (rs12191786) polymorphisms of toll like receptor-2 gene with the two clinical forms of apical periodontitis: acute apical abscess (AAA) and asymptomatic apical periodontitis (AAP). MATERIALS AND

methodThere were 50 patients with AAA as case group and 50 with AAP as control group. Genotyping was done using Tetra-ARMS (amplification refractory mutation system) PCR.

resultsHeterozygous genotype of Arg677Trp polymorphism was associated with risk of AAA (OR=1.9, 95% CI: 0.7-5.5,

conclusionArg677Trp polymorphism of TLR-2 rendered a higher risk for the development of abscesses in apical periodontitis. It is recommended to explore role of this polymorphism in other populations.

Indexed as

Acute apical abscessPeriapical AbscessPolymorphismToll like receptor-2

Identifiers

PMID29854884
PMCPMC5960730
OpenAlexW2811457840

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.