Evidence map›Paper›PMID 29854823›Full record

ArticleJournal of diabetes research2018

A Mouse Model of Beta-Cell Dysfunction as Seen in Human Type 2 Diabetes.

Jacqueline H Parilla, Joshua R Willard, Breanne M Barrow, Sakeneh Zraika

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 24 citations in OpenAlex.

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  11. Ginsenoside Rb1 Promotes Hepatic Glycogen Synthesis to Ameliorate T2DM Through 15-PGDH/PGEDiabetes, metabolic syndrome and obesity : targets and therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jacqueline H ParillaVeterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
Joshua R WillardVeterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
Breanne M BarrowVeterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
Sakeneh ZraikaVeterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.ORCID 0000-0003-4831-7034
University of Washington · USVA Puget Sound Health Care System · US

Funding

Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4M
Diabetes, Obesity and Metabolism Training ProgramT32DK007247 · NIDDK · UNIVERSITY OF WASHINGTON · PI GREGORY J MORTON, KRISTINA Marie UTZSCHNEIDER · 1986 to 2026
$10.0M
Impact of Neprilysin on Islet FunctionR01DK098506 · NIDDK · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI ZRAIKA, SAKENEH · 2013 to 2017
$1.5M
NIDDK NIH HHS P30 DK017047NIDDK NIH HHS R01 DK098506NIDDK NIH HHS T32 DK007247
6 · The paper itself

Abstract

Loss of first-phase insulin release is an early pathogenic feature of type 2 diabetes (T2D). Various mouse models exist to study T2D; however, few recapitulate the early

Indexed as

AnimalsBlood GlucoseDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Disease Models, AnimalGlucose Tolerance TestInsulinInsulin ResistanceInsulin-Secreting CellsMicePancreasBlood GlucoseInsulin

Identifiers

PMID29854823
PMCPMC5952555
OpenAlexW2801428092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.