Evidence map›Paper›PMID 29854820›Full record

ArticleJournal of diabetes research2018

To Predict the Requirement of Pharmacotherapy by OGTT Glucose Levels in Women with GDM Classified by the IADPSG Criteria.

Gülen Yerlikaya, Veronica Falcone, Tina Stopp, Martina Mittlböck, Andrea Tura, Peter Husslein, Wolfgang Eppel, Christian S Göbl

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Prediction Models for Maternal and Offspring Short- and Long-Term Outcomes Following Gestational Diabetes: A Systematic Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. The use of machine learning to predict pharmacological therapy in gestational diabetes: A scoping review.Diabetic medicine : a journal of the British Diabetic Association · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Gülen YerlikayaDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.
Veronica FalconeDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.
Tina StoppDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.
Martina MittlböckCenter of Medical Statistics, Informatics, and Intelligent Systems, Section for Clinical Biometrics, Medical University of Vienna, Vienna, Austria.
Andrea TuraMetabolic Unit, Institute of Neuroscience, National Research Council, Padova, Italy.ORCID 0000-0003-3466-5900
Peter HussleinDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.
Wolfgang EppelDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.
Christian S GöblDepartment of Obstetrics and Gynecology, Division of Obstetrics and Feto-Naternal Medicine, Medical University of Vienna, Vienna, Austria.ORCID 0000-0002-3922-7443
Medical University of Vienna · ATNational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the association between OGTT glucose levels and requirement of pharmacotherapy in GDM patients classified by the IADPSG criteria. This study included 203 GDM patients (108 managed with lifestyle modification and 95 requiring pharmacotherapy). Clinical risk factors and OGTT glucose concentrations at 0 (G0), 60 (G60), and 120 min (G120) were collected. OGTT glucose levels were significantly associated with the later requirement of pharmacotherapy (ROC-AUC: 71.1, 95% CI: 63.8-78.3). Also, the combination of clinical risk factors (age, BMI, parity, and pharmacotherapy in previous gestation) showed an acceptable predictive accuracy (ROC-AUC: 72.1, 95% CI: 65.0-79.2), which was further improved when glycemic parameters were added (ROC-AUC: 77.5, 95% CI: 71.5-83.9). Random forest analysis revealed the highest variable importance for G0, G60, and age. OGTT glucose measures in addition to clinical risk factors showed promising properties for risk stratification in GDM patients classified by the recently established IADPSG criteria.

Indexed as

AdultBlood GlucoseDiabetes, GestationalFemaleGlucose Tolerance TestHumansHypoglycemic AgentsInsulin ResistancePregnancyBlood GlucoseHypoglycemic Agents

Identifiers

PMID29854820
PMCPMC5964564
OpenAlexW2802175753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.