Evidence map›Paper›PMID 29854623›Full record

ArticleToxicology reports2018

Effects of formaldehyde exposure on the development of pulmonary fibrosis induced by bleomycin in mice.

Mayara Peres Leal, Robson Alexandre Brochetti, Aline Ignácio, Niels Olsen Saraiva Câmara, Renata Kelly da Palma, Luis Vicente Franco de Oliveira, Daniela de Fátima Teixeira da Silva, Adriana Lino-Dos-Santos-Franco

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. A Review of CXCL1 in Cardiac Fibrosis.Frontiers in cardiovascular medicine · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Occupational Exposure to Formaldehyde and Cancer Risk Assessment in an Anatomy Laboratory.International journal of environmental research and public health · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mayara Peres LealPost Graduate Program in Biophotonics Applied to Health Sciences, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Robson Alexandre BrochettiPost Graduate Program in Biophotonics Applied to Health Sciences, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Aline IgnácioDepartment of Immunology, University of São Paulo, São Paulo, Brazil.
Niels Olsen Saraiva CâmaraDepartment of Immunology, University of São Paulo, São Paulo, Brazil.
Renata Kelly da PalmaPost Graduate Program in Science of rehabilitation, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Luis Vicente Franco de OliveiraPost Graduate Program in Science of rehabilitation, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Daniela de Fátima Teixeira da SilvaPost Graduate Program in Biophotonics Applied to Health Sciences, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Adriana Lino-Dos-Santos-FrancoPost Graduate Program in Biophotonics Applied to Health Sciences, University Nove de Julho (UNINOVE), São Paulo, Brazil.
Universidade Nove de Julho · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental and Occupational pollution has been extensively studied because of its serious implications on the human health. Formaldehyde (FA) is a pollutant widely employed in several industries and also in anatomy, pathology and histology laboratories. Studies have shown the correlation between FA exposure and development or worsening of asthma. However, the effect of FA exposure on the pulmonary fibrosis (PF) is unknown. PF is a progressive and chronic lung disease with high incidence and considerable morbidity and mortality. Few studies have shown a worsening of PF after pollutants exposure such as ozone and nitrogen dioxide. Therefore, our objective was to assess the effects of FA on the PF. Male mice C57BL6 were treated or not with bleomycin (1,5 U/kg) and exposed or not to FA inhalation (0.92 mg/m

Indexed as

Collagen productionCytokinesFormaldehyde exposureLung elastanceLung inflammationPulmonary fibrosis

Identifiers

PMID29854623
PMCPMC5977414
OpenAlexW2796104594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.