Evidence map›Paper›PMID 29854039›Full record

ReviewPain research & management2018

Medicinal Plants of the Family Lamiaceae in Pain Therapy: A Review.

Cristina M Uritu, Cosmin T Mihai, Gabriela-Dumitrita Stanciu, Gianina Dodi, Teodora Alexa-Stratulat, Andrei Luca, Maria-Magdalena Leon-Constantin, Raluca Stefanescu, Veronica Bild, Silvia Melnic and 1 more

Abstract readReview
In one paragraph

Review in Pain research & management, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 120 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
120citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

120 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Effect of essential oils onParasitology · 2020
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Biomimetic Synthesis of Seven Halenaquinone Meroterpenoids.Journal of the American Chemical Society · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Integrated Evaluation ofInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Evaluating the Therapeutic Effects ofPediatric health, medicine and therapeutics · 2026
    Review
  18. Article
  19. Article
  20. A Comprehensive Review on Anxiolytic Effect ofFood science & nutrition · 2025
    Review

60 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cristina M Uritu"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Cosmin T Mihai"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Gabriela-Dumitrita Stanciu"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Gianina Dodi"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-5551-6077
Teodora Alexa-Stratulat"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2696-9568
Andrei Luca"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-3628-4637
Maria-Magdalena Leon-Constantin"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Raluca Stefanescu"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Veronica Bild"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.
Silvia MelnicInstitute of Chemistry, Academy of Sciences of Moldova, MD-2028 Chisinau, Moldova.ORCID 0000-0002-8498-024X
Bogdan I Tamba"Grigore T. Popa" University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-9868-1999

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, numerous side effects of synthetic drugs have lead to using medicinal plants as a reliable source of new therapy. Pain is a global public health problem with a high impact on life quality and a huge economic implication, becoming one of the most important enemies in modern medicine. The medicinal use of plants as analgesic or antinociceptive drugs in traditional therapy is estimated to be about 80% of the world population. The Lamiaceae family, one of the most important herbal families, incorporates a wide variety of plants with biological and medical applications. In this study, the analgesic activity, possible active compounds of Lamiaceae genus, and also the possible mechanism of actions of these plants are presented. The data highlighted in this review paper provide valuable scientific information for the specific implications of Lamiaceae plants in pain modulation that might be used for isolation of potentially active compounds from some of these medicinal plants in future and formulation of commercial therapeutic agents.

Indexed as

PhytotherapyAnimalsHumansLamiaceaePainPlant ExtractsPlants, MedicinalPlant Extracts

Identifiers

PMID29854039
PMCPMC5964621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.