Evidence map›Paper›PMID 29853956›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2018

Pharmacological Properties of the Medical Maggot: A Novel Therapy Overview.

Litao Yan, Jin Chu, Mingshu Li, Xianfeng Wang, Junwei Zong, Xueyang Zhang, Mingzhi Song, Shouyu Wang

Abstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Procedures for determining the antimicrobial activity of maggot excretions and secretions of the green bottle fly: a narrative literature review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Defensins ofInternational journal of environmental research and public health · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Parasite-bacteria interrelationship.Parasitology research · 2020
    Review
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Litao YanDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.ORCID 0000-0002-6653-2865
Jin ChuDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Mingshu LiDepartment of Ophthalmology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xianfeng WangDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Junwei ZongDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Xueyang ZhangDepartment of Endocrinology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
Mingzhi SongDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.ORCID 0000-0002-3184-4236
Shouyu WangDepartment of Orthopaedics, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.ORCID 0000-0002-2808-0247

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade, maggot has been hailed as the miraculous "medicinal maggot" for its diverse properties, including antimicrobial, antibiofilm, anti-inflammatory, and wound healing activities. The fact that maggots show so many beneficial properties has increased the interest in these tiny larvae dramatically. Whilst there is relatively abundant clinical evidence to demonstrate the success of maggots as debridement agents, not so much emphasis has been placed on the basic science evidence, which was a combination of physical and biochemical actions. This review differs from those earlier works in that it is undertaken to provide an update of the latest scientific basis published on maggot, particularly active ingredients within maggot excretions/secretions (ES). Further investigations should focus on the isolation, identification, recombination, transgenosis, and mass production of the beneficial molecules within maggots.

Identifiers

PMID29853956
PMCPMC5960508

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.