Evidence map›Paper›PMID 29853953›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment.

Nan Liu, Yunyao Jiang, Min Xing, Baixiao Zhao, Jincai Hou, Minyee Lim, Jian Huang, Xue Luo, Li Han

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. The Effect of Moxibustion Stimulation on Local and Distal Skin Temperature in Healthy Subjects.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  4. Effect of Moxibustion on Testosterone Secretion and Apoptosis of Spermatogenic Cells in Aging Rats.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  5. An Introduction to the Analysis of Single-Cell RNA-Sequencing Data.Molecular therapy. Methods & clinical development · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Nan LiuSchool of Clinical Medicine, Beijing University of Chinese Medicine, Beijing 10029, China.ORCID 0000-0003-4133-1706
Yunyao JiangInstitute of Basic Medical Sciences, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China.ORCID 0000-0001-7103-9365
Min XingSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Baixiao ZhaoSchool of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID 0000-0003-3644-6883
Jincai HouJing-Jin-Ji Joint Innovation Pharmaceutical (Beijing) Co., Ltd., Beijing 100083, China.
Minyee LimInternational School, Beijing University of Chinese Medicine, Beijing 100029, China.
Jian HuangBeijing Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100029, China.
Xue LuoSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.
Li HanSchool of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China.ORCID 0000-0003-3436-2811
Beijing University of Chinese Medicine · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging is closely connected with death, progressive physiological decline, and increased risk of diseases, such as cancer, arteriosclerosis, heart disease, hypertension, and neurodegenerative diseases. It is reported that moxibustion can treat more than 300 kinds of diseases including aging related problems and can improve immune function and physiological functions. The digital gene expression profiling of aged mice with or without moxibustion treatment was investigated and the mechanisms of moxibustion in aged mice were speculated by gene ontology and pathway analysis in the study. Almost 145 million raw reads were obtained by digital gene expression analysis and about 140 million (96.55%) were clean reads. Five differentially expressed genes with an adjusted

Identifiers

PMID29853953
PMCPMC5954890
OpenAlexW2800467109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.