Evidence map›Paper›PMID 29853916›Full record

ArticleStem cells international2018

Human Bone Marrow Contains Mesenchymal Stromal Stem Cells That Differentiate In Vitro into Contractile Myofibroblasts Controlling T Lymphocyte Proliferation.

Yves Lecarpentier, Olivier Schussler, Antonija Sakic, José Maria Rincon-Garriz, Priscilla Soulie, Marie-Luce Bochaton-Piallat, Vincent Kindler

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Mesodermal Derivatives of Pluripotent Stem Cells Route to Scarless Healing.International journal of molecular sciences · 2023
    Review
  4. Article
  5. Review
  6. Review
  7. Local and Remote Effects of Mesenchymal Stem Cell Administration on Skin Wound Regeneration.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021
    Article
  8. Review
  9. Effects of CD4Experimental and therapeutic medicine · 2020
    Article
  10. Lung-resident mesenchymal stromal cells are tissue-specific regulators of lung homeostasis.American journal of physiology. Lung cellular and molecular physiology · 2020
    Review
  11. Article
  12. Bone marrow mesenchymal stem cells differentiate into intestinal epithelioid cells through the ERK1/2 pathway.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2020
    Article
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yves LecarpentierCentre de Recherche Clinique, Grand Hôpital de l'Est Francillien, 77104 Meaux, France.ORCID 0000-0003-0437-4862
Olivier SchusslerDepartment of Cardiovascular Surgery, Research Laboratory, University Hospitals, Faculty of Medicine, Geneva, Switzerland.
Antonija SakicDepartment of Pathology and Immunology, Centre Médical Universitaire Geneva Faculty of Medicine, Geneva, Switzerland.
José Maria Rincon-GarrizDepartment of Specialties in Medicine, Hematology Service, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.
Priscilla SoulieDepartment of Histology, Centre Médical Universitaire Geneva Faculty of Medicine, Geneva, Switzerland.
Marie-Luce Bochaton-PiallatDepartment of Pathology and Immunology, Centre Médical Universitaire Geneva Faculty of Medicine, Geneva, Switzerland.
Vincent KindlerDepartment of Specialties in Medicine, Hematology Service, Geneva University Hospitals, Faculty of Medicine, Geneva, Switzerland.ORCID 0000-0002-5349-1857
University Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mesenchymal stromal stem cells (MSC) that reside in the bone marrow (BM) can be amplified in vitro. In 2-dimension (D) cultures, MSC exhibit a morphology similar to fibroblasts, are able to inhibit T lymphocyte and natural killer cell proliferation, and can be differentiated into adipocytes, chondrocytes, or osteoblasts if exposed to specific media. Here we show that medullar MSC cultured in 2D formed an adherent stroma of cells expressing well-organized microfilaments containing

Identifiers

PMID29853916
PMCPMC5949154
OpenAlexW2801890181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.