Evidence map›Paper›PMID 29853879›Full record

ArticleInternational journal of endocrinology2018

Impact of Long-Acting Somatostatin Analogues on Glucose Metabolism in Acromegaly: A Hospital-Based Study.

Ming Shen, Meng Wang, Wenqiang He, Min He, Nidan Qiao, Zengyi Ma, Zhao Ye, Qilin Zhang, Yichao Zhang, Yeping Yang and 12 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Insulin Resistance in Patients With Acromegaly.Frontiers in endocrinology · 2019
    Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Ming ShenDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Meng WangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0002-8941-8061
Wenqiang HeDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Min HeDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
Nidan QiaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Zengyi MaDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Zhao YeDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Qilin ZhangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yichao ZhangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yeping YangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yanjiao CaiDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yakupujiang ABuDuoReYiMuDepartment of Endocrinology and Metabolism, The Second People's Hospital of Kashi, Xinjiang Uygur Autonomous Region 844000, China.
Yun LuDepartment of Nuclear Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China.
Bin LuDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
Xuefei ShouDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yongfei WangDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Hongying YeDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yiming LiDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0002-1828-8765
Shiqi LiDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Yao ZhaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.
Xiaoyun CaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0002-7174-4731
Zhaoyun ZhangDepartment of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.ORCID 0000-0001-5366-1353
Fudan University · CNPeople's Hospital of Xinjiang Uygur Autonomous Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the change in glucose tolerance in treatment-naïve patients with acromegaly after administration of SSA and to identify predictive factors of glucose impairment during SSA therapy.

methodsOral glucose tolerance testing (OGTT) was performed on 64 newly diagnosed and treatment-naïve patients with acromegaly both at pretreatment and 3 months after initiation of treatment with long-acting SSA. Insulin resistance (IR) was assessed by homeostatic model assessment- (HOMA-) IR and IS

resultsPretreatment, 19, 24, and 21 patients were categorized as having normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and diabetes mellitus (DM), respectively. Posttreatment, IR, represented by IS

conclusionsThe deterioration of glucose metabolism induced by SSA treatment is caused by the less reduction of GH and the more inhibition of insulin secretion, which can be predicted by the baseline BG

Identifiers

PMID29853879
PMCPMC5944271
OpenAlexW2800414805

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.