SynthesisNeural plasticity2018
The Activation of the Mirror Neuron System during Action Observation and Action Execution with Mirror Visual Feedback in Stroke: A Systematic Review.
Synthesis in Neural plasticity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 57 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Mirror Therapy Combined With Contralaterally Controlled Functional Electrical Stimulation on Functional Recovery and Neuroplasticity in Patients With Peripheral Nerve Injury
Comparison of the Effects of Mirror Therapy Integrated With Electrical Stimulation and Motor Imagery on Cortical Modulations in Patients With Peripheral Nerve Injury and Healthy Adults
Non-Immersive Virtual Reality (MindMotion™ GO) Improves Upper Limb Motor Function in Chronic Left MCA Stroke: A Randomized Controlled Trial
Who cites it
57 citing papers in PubMed, 4 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Virtual Reality Enhanced Exercise Training in Upper Limb Function of Patients With Stroke: Meta-Analytic Study.Journal of medical Internet research · 2025Pooled it
- Examining the effectiveness of virtual, augmented, and mixed reality (VAMR) therapy for upper limb recovery and activities of daily living in stroke patients: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2022Pooled it
- The Effects of Action Observation Therapy as a Rehabilitation Tool in Parkinson's Disease Patients: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Immediate and long-term effects of BCI-based rehabilitation of the upper extremity after stroke: a systematic review and meta-analysis.Journal of neuroengineering and rehabilitation · 2020Pooled it
- Cortical hemodynamic responses during action observation with and without audiovisual stimuli: a randomized controlled experimental trial.Experimental brain research · 2026Trial
- Evidence of mirror therapy for recruitment of ipsilateral motor pathways in stroke recovery: A resting fMRI study.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024Trial
- Use of recognition of laterality through implicit motor imagery for the improvement of postural control and balance in subacute stroke patients: a randomized controlled study.Revista de neurologia · 2022Trial
- Effects of Meaningful Action Observation Therapy on Occupational Performance, Upper Limb Function, and Corticospinal Excitability Poststroke: A Double-Blind Randomized Control Trial.Neural plasticity · 2022Trial
- The Priming Effects of Mirror Visual Feedback on Bilateral Task Practice: A Randomized Controlled Study.Occupational therapy international · 2019Trial
- EEG Biomarkers During Upper-Limb Action Observation Therapy for Stroke Rehabilitation: A Scoping Review.Annals of biomedical engineering · 2026Review
- The Moderating Role of Virtual Arm Embodiment for Upper Limb Rehabilitation in Stroke Patients with Proprioceptive Deficit: A Pilot Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Mirror Neuron System and Upper-Limb EMG Activity During Reaching Imitation in Stroke Survivors: Comparing Outcomes After Observing Normal vs. Aberrant Movements.NeuroRehabilitation · 2026Article
- The effects of mirror visual feedback involved network priming on embodiment perception in healthy subjects: a proof-of-concept study.Frontiers in neuroscience · 2026Article
- Topography of Cortical Activation with Mirror Visual Feedback and Electromyography-Triggered Electrical Stimulation: A Functional Near-Infrared Spectroscopy Study in Healthy Older Adults.Brain sciences · 2025Article
- Action Observation Training for Upper Limb Stroke Rehabilitation: A Pilot Study on the Role of Attention.Journal of clinical medicine · 2025Article
- Impact of Observation Duration in Action Observation Therapy: Manual Dexterity, Mirror Neuron System Activity, and Subjective Psychomotor Effort in Healthy Adults.Brain sciences · 2025Article
- Motor and parietal cortex activity responses to mirror visual feedback in patients with subacute stroke: An EEG study.Clinical neurophysiology practice · 2025Article
- Identification of Subtypes of Post-Stroke and Neurotypical Gait Behaviors Using Neural Network Analysis of Gait Cycle Kinematics.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Comparison of Brain Activation Between Different Modes of Motor Acquisition: A Functional Near-Infrared Study.Brain and behavior · 2025Article
- The Role of Mirror Therapy in the Rehabilitation of the Upper Limb's Motor Deficits After Stroke: Narrative Review.Journal of clinical medicine · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the concurrent and training effects of action observation (AO) and action execution with mirror visual feedback (MVF) on the activation of the mirror neuron system (MNS) and its relationship with the activation of the motor cortex in stroke individuals. Methods: A literature search using CINAHL, PubMed, PsycINFO, Medline, Web of Science, and SCOPUS to find relevant studies was performed. Results: A total of 19 articles were included. Two functional magnetic resonance imaging (fMRI) studies reported that MVF could activate the ipsilesional primary motor cortex as well as the MNS in stroke individuals, whereas two other fMRI studies found that the MNS was not activated by MVF in stroke individuals. Two clinical trials reported that long-term action execution with MVF induced a shift of activation toward the ipsilesional hemisphere. Five fMRI studies showed that AO activated the MNS, of which, three found the activation of movement-related areas. Five electroencephalography (EEG) studies demonstrated that AO or MVF enhanced mu suppression over the sensorimotor cortex. Conclusions: MVF may contribute to stroke recovery by revising the interhemispheric imbalance caused by stroke due to the activation of the MNS. AO may also promote motor relearning in stroke individuals by activating the MNS and motor cortex.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.