Evidence map›Paper›PMID 29853806›Full record

ReviewContrast media & molecular imaging2018

Overview and Critical Appraisal of Arterial Spin Labelling Technique in Brain Perfusion Imaging.

Amirah Alsaedi, David Thomas, Sotirios Bisdas, Xavier Golay

Abstract readReview
In one paragraph

Review in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  11. In Vivo Imaging of Rat Vascularity with FDG-Labeled Erythrocytes.Pharmaceuticals (Basel, Switzerland) · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amirah AlsaediDepartment of Radiology Technology, Taibah University, Medina, Saudi Arabia.ORCID 0000-0002-8936-7479
David ThomasDepartment of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, UK.
Sotirios BisdasDepartment of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, UK.ORCID 0000-0001-9930-5549
Xavier GolayDepartment of Brain Repair & Rehabilitation, UCL Institute of Neurology, London, UK.

Funding

Medical Research Council MR/M009106/1
6 · The paper itself

Abstract

Arterial spin labelling (ASL) allows absolute quantification of CBF via a diffusible intrinsic tracer (magnetically labelled blood water) that disperses from the vascular system into neighbouring tissue. Thus, it can provide absolute CBF quantification, which eliminates the need for the contrast agent, and can be performed repeatedly. This review will focus on the common ASL acquisition techniques (continuous, pulsed, and pseudocontinuous ASL) and how ASL image quality might be affected by intrinsic factors that may bias the CBF measurements. We also provide suggestions to mitigate these risks, model appropriately the acquired signal, increase the image quality, and hence estimate the reliability of the CBF, which consists an important noninvasive biomarker. Emerging methodologies for extraction of new ASL-based biomarkers, such as arterial arrival time (AAT) and arterial blood volume (aBV), will be also briefly discussed.

Indexed as

Cerebrovascular CirculationSpin LabelsAnimalsArteriesBiomarkersBrainHumansModels, TheoreticalPerfusion ImagingBiomarkersSpin Labels

Identifiers

PMID29853806
PMCPMC5964483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.