Evidence map›Paper›PMID 29852942›Full record

ReviewSeminars in nuclear medicine2018

Innovations in Instrumentation for Positron Emission Tomography.

Eric Berg, Simon R Cherry

Abstract readReview
In one paragraph

Review in Seminars in nuclear medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. High-efficiency [EJNMMI radiopharmacy and chemistry · 2025
    Article
  9. Radiation Detectors and Sensors in Medical Imaging.Sensors (Basel, Switzerland) · 2024
    Review
  10. Review
  11. SyntheticRSC medicinal chemistry · 2024
    Review
  12. Advances of radiolabeled GRPR ligands for PET/CT imaging of cancers.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Optimization of the Acquisition Time and Injected Dose ofWorld journal of nuclear medicine · 2023
    Article
  18. New Insights and Potential Therapeutic Interventions in Metabolic Diseases.International journal of molecular sciences · 2023
    Review
  19. Article
  20. Contribution of Intravital Neuroimaging to Study Animal Models of Multiple Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eric BergDepartment of Biomedical Engineering, University of California, Davis, CA.
Simon R CherryDepartment of Biomedical Engineering, University of California, Davis, CA.; Department of Radiology, University of California, Davis, CA. Electronic address: srcherry@ucdavis.edu.

Funding

EXPLORER: Changing the Molecular Imaging Paradigm with Total Body PETR01CA206187 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BADAWI, RAMSEY D., CHERRY, SIMON R · 2015 to 2019
$15.5M
Research at the interface of optical and ionizing radiation for innovative cancer imaging and therapyR35CA197608 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHERRY, SIMON R · 2015 to 2021
$4.9M
Innovative Silicon Photomultiplier Technologies for Small-Animal PETR01EB019439 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHERRY, SIMON R · 2015 to 2018
$1.4M
NCI NIH HHS R01 CA206187NCI NIH HHS R35 CA197608NIBIB NIH HHS R01 EB019439
6 · The paper itself

Abstract

PET scanners are sophisticated and highly sensitive biomedical imaging devices that can produce highly quantitative images showing the 3-dimensional distribution of radiotracers inside the body. PET scanners are commonly integrated with x-ray CT or MRI scanners in hybrid devices that can provide both molecular imaging (PET) and anatomical imaging (CT or MRI). Despite decades of development, significant opportunities still exist to make major improvements in the performance of PET systems for a variety of clinical and research tasks. These opportunities stem from new ideas and concepts, as well as a range of enabling technologies and methodologies. In this paper, we review current state of the art in PET instrumentation, detectors and systems, describe the major limitations in PET as currently practiced, and offer our own personal insights into some of the recent and emerging technological innovations that we believe will impact the field. Our focus is on the technical aspects of PET imaging, specifically detectors and system design, and the opportunity and necessity to move closer to PET systems for diagnostic patient use and in vivo biomedical research that truly approach the physical performance limits while remaining mindful of imaging time, radiation dose, and cost. However, other key endeavors, which are not covered here, including innovations in reconstruction and modeling methodology, radiotracer development, and expanding the range of clinical and research applications, also will play an equally important, if not more important, role in defining the future of the field.

Indexed as

InventionsEquipment DesignHumansImage Processing, Computer-AssistedPositron-Emission TomographySignal-To-Noise Ratio

Identifiers

PMID29852942
PMCPMC5986096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.