Evidence map›Paper›PMID 29852867›Full record

ReviewCurrent protein & peptide science2018

The Development of Peptide-based Antimicrobial Agents against Dengue Virus.

Yen-Wei Huang, Chun-Ting Lee, Ta-Chen Wang, Yun-Chung Kao, Chih-Hui Yang, Yu-Mei Lin, Keng-Shiang Huang

Open access · bronzeAbstract readReview
In one paragraph

Review in Current protein & peptide science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Update on antimicrobial peptides: key elements inThe Journal of general virology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yen-Wei HuangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Chun-Ting LeeThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Ta-Chen WangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Yun-Chung KaoThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Chih-Hui YangDepartment of Biological Science and Technology, I-Shou University, Kaohsiung, Taiwan.
Yu-Mei LinThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
Keng-Shiang HuangThe School of Chinese Medicine for Post-Baccalaureate, I-Shou University, Kaohsiung, Taiwan.
I-Shou University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever has become an imminent threat to international public health because of global warming and climate change. The World Health Organization proclaimed that more than 50% of the world's population is at risk of dengue virus (DENV) infection. Therefore, developing a clinically approved vaccine and effective therapeutic remedy for treating dengue fever is imperative. Peptide drug development has become a novel pharmaceutical research field. This article reviews various peptidesbased antimicrobial agents targeting three pathways involved in the DENV lifecycle. Specifically, they are peptide vaccines from immunomodulation, peptide drugs that inhibit virus entry, and peptide drugs that interfere with viral replication. Many antiviral peptide studies against DENV have been conducted in animal model trials, and progression to clinical trials for these promising peptide drugs is anticipated.

Indexed as

AnimalsAntimicrobial Cationic PeptidesAntiviral AgentsDengueDengue VaccinesDengue VirusDrug DiscoveryHumansMolecular Targeted TherapyPeptidesVaccines, SubunitVaccines, SyntheticVirus ReplicationAntimicrobial Cationic PeptidesAntiviral AgentsDengue VaccinesPeptidesVaccines, SubunitVaccines, Syntheticantimicrobial agentsclinical trialsDengue feverdengue viruspeptide drugpeptide vaccine.

Identifiers

PMID29852867
PMCPMC6446661
OpenAlexW2806795375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.