Evidence map›Paper›PMID 29852331›Full record

ArticleClinical biomechanics (Bristol, Avon)2018

American Society of Biomechanics Clinical Biomechanics Award 2017: Non-anatomic graft geometry is linked with asymmetric tibiofemoral kinematics and cartilage contact following anterior cruciate ligament reconstruction.

Michael F Vignos, Jarred M Kaiser, Geoffrey S Baer, Richard Kijowski, Darryl G Thelen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical biomechanics (Bristol, Avon), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Increase in cartilage degeneration in all knee compartments after failed ACL reconstruction at 4 years of follow-up.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
    Article
  5. Review
  6. Article
  7. Article
  8. ACL Reconstruction Graft Angle and Outcomes: Transtibial vs Anteromedial Reconstruction.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2020
    Article
  9. Article
  10. Annals of translational medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael F VignosDepartment of Mechanical Engineering, University of Wisconsin - Madison, 1513 University Avenue, Madison, WI 53706, USA. Electronic address: mvignos@wisc.edu.
Jarred M KaiserDepartment of Mechanical Engineering, University of Wisconsin - Madison, 1513 University Avenue, Madison, WI 53706, USA; Department of Mechanical Engineering, Boston University, 110 Cummington Mall, Boston, MA 02215, USA.
Geoffrey S BaerDepartment of Orthopedics and Rehabilitation, University of Wisconsin - Madison, 1685 Highland Avenue, Madison, WI 53705, USA.
Richard KijowskiDepartment of Radiology, University of Wisconsin - Madison, 600 Highland Avenue, Madison, WI 53792, USA.
Darryl G ThelenDepartment of Mechanical Engineering, University of Wisconsin - Madison, 1513 University Avenue, Madison, WI 53706, USA; Department of Orthopedics and Rehabilitation, University of Wisconsin - Madison, 1685 Highland Avenue, Madison, WI 53705, USA; Department of Biomedical Engineering, University of Wisconsin - Madison, 1415 Engineering Drive, Madison, WI 53706, USA. Electronic address: dgthelen@wisc.edu.
University of Wisconsin–Madison · USBoston University · US

Funding

A Multi-Scale Modeling Construct of Knee Mechanics following ACL ReconstructionU01EB015410 · NIBIB · REHABILITATION INSTITUTE OF CHICAGO D/B/A SHIRLEY RYAN ABILITYLAB · PI DHAHER, YASIN YOUSEF, THELEN, DARRYL G · 2013 to 2016
$2.0M
NIBIB NIH HHS U01 EB015410
6 · The paper itself

Abstract

backgroundAbnormal knee mechanics may contribute to early cartilage degeneration following anterior cruciate ligament reconstruction. Anterior cruciate ligament graft geometry has previously been linked to abnormal tibiofemoral kinematics, suggesting this parameter may be important in restoring normative cartilage loading. However, the relationship between graft geometry and cartilage contact is unknown.

methodsStatic MR images were collected and segmented for eighteen subjects to obtain bone, cartilage, and anterior cruciate ligament geometries for their reconstructed and contralateral knees. The footprint locations and orientation of the anterior cruciate ligament were calculated. Volumetric, dynamic MR imaging was also performed to measure tibiofemoral kinematics, cartilage contact location, and contact sliding velocity while subjects performed loaded knee flexion-extension. Multiple linear regression was used to determine the relationship between non-anatomic graft geometry and asymmetric knee mechanics.

findingsNon-anatomic graft geometry was related to asymmetric knee mechanics, with the sagittal plane graft angle being the best predictor of asymmetry. A more vertical sagittal graft angle was associated with greater anterior tibial translation (β = 0.11mmdeg, P = 0.049, R

interpretationThis study provides evidence that non-anatomic graft geometry is linked to asymmetric knee mechanics, suggesting that restoring native anterior cruciate ligament geometry may be important to mitigate the risk of early cartilage degeneration in these patients.

Indexed as

Magnetic Resonance ImagingAdultAnterior Cruciate LigamentAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionAwards and PrizesBiomechanical PhenomenaCartilageFemaleFemurHumansKnee InjuriesKnee JointLinear ModelsMaleMiddle AgedAnterior cruciate ligament graftAnterior cruciate ligament reconstructionCartilageKneeMRIOsteoarthritis

Identifiers

PMID29852331
PMCPMC6004264
OpenAlexW2801306530

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.