Trial reportBehaviour research and therapy2018
Change in anxiety sensitivity and substance use coping motives as putative mediators of treatment efficacy among substance users.
Trial report in Behaviour research and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- A systematic review and meta-analysis of psychosocial interventions for persons with comorbid anxiety and substance use disorders.Journal of substance use and addiction treatment · 2024Pooled it
- Augmenting the efficacy of benzodiazepine taper with telehealth-delivered cognitive behavioral therapy for anxiety disorders in patients using prescription opioids: A pilot randomized controlled trial.Contemporary clinical trials · 2023Trial
- Computer-delivered personalized feedback intervention for hazardous drinkers with elevated anxiety sensitivity: A pilot randomized controlled trial.Behaviour research and therapy · 2021Trial
- Sex Differences in the Synergistic Effects of Distress Intolerance and Anxiety Sensitivity on Alcohol Use and Related Problems Among Black Adults who Smoke.Journal of racial and ethnic health disparities · 2025Article
- Digital relapse prevention plan for substance use disorders: study protocol for a multicentre randomised controlled trial.BMJ health & care informatics · 2025Article
- Irritable Bowel Syndrome (IBS) and Smoking: An Evaluation of IBS symptom severity and anxiety sensitivity among adults in the United States.Addictive behaviors · 2025Review
- Longitudinal associations between anxiety sensitivity and substance use in adolescents: Mediation by depressive affect.Experimental and clinical psychopharmacology · 2024Article
- Higher perceived stress during admission is associated with shorter retention in short-term residential substance use disorder treatment.Addictive behaviors reports · 2023Article
- Prospective Associations Between Anxiety Sensitivity, Distress Intolerance, Depressive Symptoms, and Indices of Alcohol and Cannabis Use Among Veterans.Journal of studies on alcohol and drugs · 2023Article
- Reciprocal longitudinal associations between anxiety sensitivity and alcohol consumption/problems across adolescence: Examining anxiety as a mediator and race/ethnicity as a moderator.Behaviour research and therapy · 2021Article
- Motives for Substance Use in Daily Life: A Systematic Review of Studies Using Ecological Momentary Assessment.Clinical psychological science : a journal of the Association for Psychological Science · 2021Article
- Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020Article
- The Role of Affect in Psychosocial Treatments for Substance Use Disorders.Current addiction reports · 2020Article
- Intraindividual change in anxiety sensitivity and alcohol use severity 12-months following smoking cessation treatment.Behaviour research and therapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveAnxiety sensitivity and coping motives for substance use are processes implicated in anxiety and substance use disorder (SUD) comorbidity, and are malleable treatment targets. Little is known about whether changes in anxiety sensitivity or coping motives during cognitive behavioral therapy (CBT) for anxiety disorders (with or without CBT for SUD) mediate substance use outcomes among patients with comorbid anxiety disorders and SUD. We examined whether changes in anxiety sensitivity and coping motives during treatment for comorbid SUD and anxiety disorders (either CBT for SUD only or CBT for SUD and anxiety disorders) were associated with substance use outcomes.
methodsRepeated measurements of anxiety sensitivity and coping motives throughout treatment were examined from a randomized clinical trial comparing usual, CBT-based treatment at a substance use disorder specialty clinic (UC) to that usual care plus a brief CBT for anxiety program for patients with comorbid anxiety and substance use disorders (CALM ARC).
resultsAnxiety sensitivity decline during treatment was significantly steeper among those who received CALM ARC than those in UC. Decreases in anxiety sensitivity mediated the effect of treatment group on alcohol use following treatment such that the greater reduction in anxiety sensitivity in CALM ARC explained the superior outcomes for alcohol use in CALM ARC compared to UC. Declines in substance use coping motives were not observed in either condition, and did not differ between CALM ARC and UC. Thus, declines in coping motives did not mediate substance use after treatment.
conclusionsThese findings provide preliminary evidence suggesting alcohol use outcomes were related to decreasing anxiety sensitivity rather than decreasing coping motives. Implications and future directions are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.