Evidence map›Paper›PMID 29851504›Full record

ArticleAIDS patient care and STDs2018

PositiveLinks: A Mobile Health Intervention for Retention in HIV Care and Clinical Outcomes with 12-Month Follow-Up.

Rebecca Dillingham, Karen Ingersoll, Tabor E Flickinger, Ava Lena Waldman, Marika Grabowski, Colleen Laurence, Erin Wispelwey, George Reynolds, Mark Conaway, Wendy F Cohn

Registry-linked trialAbstract read
In one paragraph

Article in AIDS patient care and STDs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04998019 (Pragmatic Efficacy Trial of mHealth to Improve HIV Outcomes in the DC Cohort), which is not on this map. Cited by 90 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04998019 nacompletednot on this mapstarted 2022, after this paper: background citation

Pragmatic Efficacy Trial of mHealth to Improve HIV Outcomes in the DC Cohort

TypeinterventionalSponsorGeorge Washington UniversityRan2022 to 2025Enrolled682ConditionsHIV/AIDSArmsPositiveLinks
3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rebecca Dillingham1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
Karen Ingersoll2 Department of Psychiatry and Neurobehavioral Sciences, University of Virginia School of Medicine , Charlottesville, Virginia.
Tabor E Flickinger1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
Ava Lena Waldman1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
Marika Grabowski1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
Colleen Laurence1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
Erin Wispelwey1 1Department of Medicine, University of Virginia School of Medicine , Charlottesville, Virginia.
George Reynolds3 Health Decision Technologies , Oakland, California.
Mark Conaway4 Department of Public Health Sciences, University of Virginia School of Medicine , Charlottesville, Virginia.
Wendy F Cohn4 Department of Public Health Sciences, University of Virginia School of Medicine , Charlottesville, Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mobile health interventions may help People Living with HIV (PLWH) improve engagement in care. We designed and piloted PositiveLinks, a clinic-affiliated mobile intervention for PLWH, and assessed longitudinal impact on retention in care and viral suppression. The program was based at an academic Ryan White Clinic serving a nonurban population in Central Virginia. The PL intervention included a smartphone app that connected participants to clinic staff and provided educational resources, daily queries of stress, mood and medication adherence, weekly quizzes, appointment reminders, and a virtual support group. Outcomes were analyzed using McNemar's tests for HRSA-1, visit constancy, and viral suppression and nonparametric Wilcoxon signed-rank tests for CD4 counts and viral loads. Of 77 participants, 63% were male, 49% black non-Hispanic, and 72% below the federal poverty level. Participants' achievement of a retention in care benchmark (HRSA-1) increased from 51% at baseline to 88% at 6 months (p < 0.0001) and 81% at 12 months (p = 0.0003). Visit constancy improved from baseline to 6 months (p = 0.016) and 12 months (p = 0.0004). Participants' mean CD4 counts increased from baseline to 6 months (p = 0.0007) and 12 months (p = 0.0005). The percentage of participants with suppressed viral loads increased from 47% at baseline to 87% at 6 months (p < 0.0001) and 79% at 12 months (p = 0.0007). This study is one of the first to demonstrate that a mobile health intervention can have a positive impact on retention in care and clinical outcomes for vulnerable PLWH. Next steps include integration with clinical practice and dissemination.

Indexed as

Continuity of Patient CareMedication AdherenceSmartphoneTelemedicineAdultAmbulatory Care FacilitiesAppointments and SchedulesCD4 Lymphocyte CountFemaleFollow-Up StudiesHIV InfectionsHumansMaleMiddle AgedReminder SystemsSelf-Help GroupsHIV/AIDSmobile healthpositive linksretention in caresmartphone app

Identifiers

PMID29851504
PMCPMC5982157

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.