Evidence map›Paper›PMID 29851267›Full record

Trial reportJournal of applied clinical medical physics2018

The impact of robustness of deformable image registration on contour propagation and dose accumulation for head and neck adaptive radiotherapy.

Lian Zhang, Zhi Wang, Chengyu Shi, Tengfei Long, X George Xu

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied clinical medical physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Lian ZhangCenter of Radiological Medical Physics, University of Science and Technology of China, Hefei, Anhui Province, China.
Zhi WangCenter of Radiological Medical Physics, University of Science and Technology of China, Hefei, Anhui Province, China.
Chengyu ShiDepartment of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Tengfei LongDepartment of Radiation Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province, China.
X George XuCenter of Radiological Medical Physics, University of Science and Technology of China, Hefei, Anhui Province, China.
University of Science and Technology of China · CNFirst Affiliated Hospital of Anhui Medical University · CNMemorial Sloan Kettering Cancer Center · USRensselaer Polytechnic Institute · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
ARCHER - An Extremely Fast Medical Radiation Dose Computing SoftwareR42EB019265 · NIBIB · VIRTUAL PHANTOMS, INC. · PI XU, XIE GEORGE · 2016 to 2018
$1.4M
NCI NIH HHS P30 CA008748NIBIB NIH HHS R42 EB019265
6 · The paper itself

Abstract

Deformable image registration (DIR) is the key process for contour propagation and dose accumulation in adaptive radiation therapy (ART). However, currently, ART suffers from a lack of understanding of "robustness" of the process involving the image contour based on DIR and subsequent dose variations caused by algorithm itself and the presetting parameters. The purpose of this research is to evaluate the DIR caused variations for contour propagation and dose accumulation during ART using the RayStation treatment planning system. Ten head and neck cancer patients were selected for retrospective studies. Contours were performed by a single radiation oncologist and new treatment plans were generated on the weekly CT scans for all patients. For each DIR process, four deformation vector fields (DVFs) were generated to propagate contours and accumulate weekly dose by the following algorithms: (a) ANACONDA with simple presetting parameters, (b) ANACONDA with detailed presetting parameters, (c) MORFEUS with simple presetting parameters, and (d) MORFEUS with detailed presetting parameters. The geometric evaluation considered DICE coefficient and Hausdorff distance. The dosimetric evaluation included D

Indexed as

Radiotherapy Planning, Computer-AssistedAdultAlgorithmsHeadHead and Neck NeoplasmsHumansImage Processing, Computer-AssistedMiddle AgedRadiographic Image Interpretation, Computer-AssistedRetrospective Studiesadaptive radiotherapycontour propagationdeformable image registrationdose accumulation

Identifiers

PMID29851267
PMCPMC6036371
OpenAlexW2805912969

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.