Evidence map›Paper›PMID 29850817›Full record

ArticleThe Journal of clinical endocrinology and metabolism2018

Risk Factors for Cardiovascular Disease Among Thyroid Cancer Survivors: Findings From the Utah Cancer Survivors Study.

Jihye Park, Brenna E Blackburn, Patricia A Ganz, Kerry Rowe, John Snyder, Yuan Wan, Vikrant Deshmukh, Michael Newman, Alison Fraser, Ken Smith and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. A Qualitative Study of Clinician Barriers and Facilitators to De-escalation of Thyroid Stimulating Hormone Suppression in Thyroid Cancer Survivors.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2026
    Article
  3. Pediatric Thyroid Cancer Multidisciplinary Team Improves Adherence of Radioactive Iodine Treatment According to National Guidelines.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Incident Cardiovascular Disease Risk among Older Asian, Native Hawaiian and Pacific Islander Breast Cancer Survivors.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Thyrotropin Suppression for Papillary Thyroid Cancer: A Physician Survey Study.Thyroid : official journal of the American Thyroid Association · 2021
    Article
  15. Article
  16. Review
  17. [The thyroid gland in old age : Physiology and pathology].Wiener medizinische Wochenschrift (1946) · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Jihye ParkHuntsman Cancer Institute, Salt Lake City, Utah.
Brenna E BlackburnHuntsman Cancer Institute, Salt Lake City, Utah.
Patricia A GanzDepartment of Health Policy and Management, UCLA Fielding School of Public Health, Los Angeles, California.
Kerry RoweIntermountain Healthcare, Salt Lake City, Utah.
John SnyderIntermountain Healthcare, Salt Lake City, Utah.
Yuan WanPedigree and Population Resource, Population Sciences, Huntsman Cancer Institute, Salt Lake City, Utah.
Vikrant DeshmukhUniversity of Utah Health Sciences Center, Salt Lake City, Utah.
Michael NewmanHuntsman Cancer Institute, Salt Lake City, Utah.
Alison FraserPedigree and Population Resource, Population Sciences, Huntsman Cancer Institute, Salt Lake City, Utah.
Ken SmithPedigree and Population Resource, Population Sciences, Huntsman Cancer Institute, Salt Lake City, Utah.
Kim HergetUtah Cancer Registry, University of Utah, Salt Lake City, Utah.
Anne C KirchhoffHuntsman Cancer Institute, Salt Lake City, Utah.
Dev AbrahamHuntsman Cancer Institute, Salt Lake City, Utah.
Jaewhan KimCollege of Health, University of Utah, Salt Lake City, Utah.
Marcus MonroeHuntsman Cancer Institute, Salt Lake City, Utah.
Mia HashibeHuntsman Cancer Institute, Salt Lake City, Utah.
University of Utah · USHuntsman Cancer Institute · USIntermountain Healthcare · USUCLA Health · US

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
Sharing statewide health data for genetic research (1 R01 RR021746-01A1)R01RR021746 · NCRR · UNIVERSITY OF UTAH · PI MINEAU, GERALDINE P · 2007 to 2009
$770k
Population-based Cohort of Endometrial Cancer Survivors in UtahR21CA185811 · NCI · UNIVERSITY OF UTAH · PI HASHIBE, MIA · 2015 to 2016
$356k
Epidemiology of testicular cancer in the Utah populationR03CA159357 · NCI · UNIVERSITY OF UTAH · PI HASHIBE, MIA · 2011 to 2012
$150k
NCI NIH HHS P30 CA042014NCI NIH HHS R03 CA159357NCI NIH HHS R21 CA185811NCRR NIH HHS R01 RR021746
6 · The paper itself

Abstract

Context: Thyroid cancer survivors are at high risk of developing multiple cardiac and vascular conditions as consequence of cancer diagnosis and treatment. However, it is still unclear how the baseline and prognostic factors, as well as cancer treatments, play a role in increasing cardiac and vascular disease risk among thyroid cancer survivors. Objective: To investigate the association between potential risk factors, treatment effects, and cardiovascular disease (CVD) outcomes in thyroid cancer survivors. Design, Setting, Patients: Primary thyroid cancer survivors, diagnosed from 1997 to 2012 (n = 3822), were identified using the statewide Utah Population Database. The medical records were used to ascertain information on risk factors and CVD outcomes. Cox proportional hazards models were used to assess the risk of CVD with baseline demographic data and clinical factors. Results: Among thyroid cancer survivors, age and year at cancer diagnosis, cancer stage, sex, baseline body mass index, baseline comorbidities, and TSH suppression therapy were significantly associated with CVD risk 1 to 5 years after cancer diagnosis. Patients who were male, overweight or obese, older at cancer diagnosis, and diagnosed with cancer since 2005 had an increased risk of CVD compared with patients who were female, had a normal body mass index, were younger at cancer diagnosis, and diagnosed with cancer from 1997 to 1999. Administration of TSH suppression therapy, distant metastases at cancer diagnosis, and a higher Charlson comorbidity index score were associated with an increased CVD risk among thyroid cancer survivors. Conclusions: Our findings suggest that examining the effect of thyroid cancer diagnosis, cancer treatment, and demographic characteristics on the risk of CVD is critical.

Indexed as

AdultAgedAged, 80 and overCancer SurvivorsCardiovascular DiseasesComorbidityDisease SusceptibilityFemaleFollow-Up StudiesHumansMaleMiddle AgedProportional Hazards ModelsRisk FactorsThyroid GlandThyroid Neoplasms

Identifiers

PMID29850817
PMCPMC6915829
OpenAlexW2805273857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.