SynthesisCerebral cortex (New York, N.Y. : 1991)2019
Human Pregenual Anterior Cingulate Cortex: Structural, Functional, and Connectional Heterogeneity.
Synthesis in Cerebral cortex (New York, N.Y. : 1991), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.
- A systematic review of associations between functional connectivity, mood and cognition in patients with irritable bowel syndrome.Brain imaging and behavior · 2026Pooled it
- Spatial migration of human reward processing with functional development: Evidence from quantitative meta-analyses.Human brain mapping · 2020Pooled it
- Memantine to Treat Social Impairment in Youths With Autism Spectrum Disorder: A Randomized Clinical Trial.JAMA network open · 2025Trial
- L-DOPA and oxytocin influence the neural correlates of performance monitoring for self and others.Psychopharmacology · 2024Trial
- Brain functional connectivity in children with developmental coordination disorder following rehabilitation intervention.Pediatric research · 2022Trial
- 2D:4D digit ratio and brain volumes in alcohol use disorder.European archives of psychiatry and clinical neuroscience · 2026Article
- Being praised and criticized in adolescents and adults: Age-related changes in neural responses to social evaluations.Developmental cognitive neuroscience · 2026Article
- Burden and risk factors of autism spectrum disorder: global study and analysis.Pediatric research · 2026Article
- Neurovariability as a signature of adaptive brain function.Brain structure & function · 2026Review
- Commonality and Variability in Functional Networks in Children Under 5 Years Old.bioRxiv : the preprint server for biology · 2026Article
- Default mode network activity is related to efficiency in a combined motion error and gambling task.Scientific reports · 2026Article
- The role of the anterior cingulate cortex in anxiety control, from circuits to disorders.Frontiers in psychiatry · 2026Review
- Gender differences in gray matter volume of the anterior cingulate cortex and suicidal ideation in patients with major depressive disorder: evidence from the REST-meta-MDD project.Translational psychiatry · 2025Article
- Circuit-Based Approaches to Understanding the Anterior Cingulate Cortex (ACC).The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Repetitive transcranial magnetic stimulation-driven modulation of unbiased functional connectivity in the supracallosal anterior cingulate cortex causally ameliorates information processing speed in amnestic mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Artificial Intelligence Networks Combining Histopathology and Machine Learning Can Extract Axon Pathology in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2025Article
- Brain and muscle chemistry in myalgic encephalitis/chronic fatigue syndrome (ME/CFS) and long COVID: a 7T magnetic resonance spectroscopy study.Molecular psychiatry · 2025Article
- Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI.Nature neuroscience · 2025Article
- Polygenic Risks for Depression and Neural Responses to Reward and Punishment in Young Adults.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Article
- Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The human pregenual anterior cingulate cortex (pACC) encompasses 7 distinct cyto- and receptorarchitectonic areas. We lack a detailed understanding of the functions in which they are involved, and stereotaxic maps are not available. We present an integrated structural/functional map of pACC based on probabilistic cytoarchitectonic mapping and meta-analytic connectivity modeling and quantitative functional decoding. Due to the restricted spatial resolution of functional imaging data relative to the microstructural parcellation, areas p24a of the callosal sulcus and p24b on the surface of the cingulate gyrus were merged into a "gyral component" (p24ab) of area p24, and areas pv24c, pd24cv, and pd24cd, located within the cingulate sulcus were merged into a "sulcal component" (p24c) for meta-analytic analysis. Area p24ab was specifically associated with interoception, p24c with the inhibition of action, and p32, which was also activated by emotion induction tasks pertaining negatively valenced stimuli, with the ability to experience empathy. Thus, area p32 could be classified as cingulate association cortex playing a crucial role in the cognitive regulation of emotion. By this spectrum of functions, pACC is a structurally and functionally heterogeneous region, clearly differing from other parts of the anterior and middle cingulate cortex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.