ArticleBioinformatics (Oxford, England)2018
GateFinder: projection-based gating strategy optimization for flow and mass cytometry.
Article in Bioinformatics (Oxford, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Automated descriptive cell type naming in flow and mass cytometry with CytoPheno.Scientific reports · 2025Article
- Integrating transcription-factor abundance with chromatin accessibility in human erythroid lineage commitment.Cell reports methods · 2022Article
- Advances in automated real-time flow cytometry for monitoring of bioreactor processes.Engineering in life sciences · 2022Review
- Single-synapse analyses of Alzheimer's disease implicate pathologic tau, DJ1, CD47, and ApoE.Science advances · 2021Article
- Feature selection revisited in the single-cell era.Genome biology · 2021Review
- Making the most of high-dimensional cytometry data.Immunology and cell biology · 2021Review
- Gut CD4Nature immunology · 2021Article
- A Cancer Biologist's Primer on Machine Learning Applications in High-Dimensional Cytometry.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2020Review
- Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities.Nature reviews. Neurology · 2020Review
- Training Novices in Generation and Analysis of High-Dimensional Human Cell Phospho-Flow Cytometry Data.Current protocols in cytometry · 2020Article
- Immune monitoring using mass cytometry and related high-dimensional imaging approaches.Nature reviews. Rheumatology · 2020Review
- Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).European journal of immunology · 2019Article
- Systemic Immunologic Consequences of Chronic Periodontitis.Journal of dental research · 2019Article
- How Clinical Flow Cytometry Rebooted Sepsis Immunology.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2019Review
- diffcyt: Differential discovery in high-dimensional cytometry via high-resolution clustering.Communications biology · 2019Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
Motivation: High-parameter single-cell technologies can reveal novel cell populations of interest, but studying or validating these populations using lower-parameter methods remains challenging. Results: Here, we present GateFinder, an algorithm that enriches high-dimensional cell types with simple, stepwise polygon gates requiring only two markers at a time. A series of case studies of complex cell types illustrates how simplified enrichment strategies can enable more efficient assays, reveal novel biomarkers and clarify underlying biology. Availability and implementation: The GateFinder algorithm is implemented as a free and open-source package for BioConductor: https://nalab.stanford.edu/gatefinder. Supplementary information: Supplementary data are available at Bioinformatics online.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.