Evidence map›Paper›PMID 29850624›Full record

ArticleJournal of immunology research2018

High-Density Lipoprotein Reduction Differentially Modulates to Classical and Nonclassical Monocyte Subpopulations in Metabolic Syndrome Patients and in LPS-Stimulated Primary Human Monocytes

Johanna L Grün, Aaron N Manjarrez-Reyna, Angélica Y Gómez-Arauz, Sonia Leon-Cabrera, Felix Rückert, José M Fragoso, Nallely Bueno-Hernández, Sergio Islas-Andrade, Guillermo Meléndez-Mier, Galileo Escobedo

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Johanna L GrünDepartment of Innate Immunity and Tolerance, Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.
Aaron N Manjarrez-ReynaLaboratory for Liver, Pancreas and Motility, Unit of Experimental Medicine, School of Medicine, National University of Mexico, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.
Angélica Y Gómez-ArauzLaboratory for Liver, Pancreas and Motility, Unit of Experimental Medicine, School of Medicine, National University of Mexico, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.
Sonia Leon-CabreraCarrera de Médico Cirujano, Unidad de Biomedicina, Facultad de Estudios Superiores-Iztacala, Universidad Nacional Autónoma de México, Avenida de los Barrios 1, 54090 Los Reyes Iztacala, MEX, Mexico.
Felix RückertDepartment of Surgery, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.ORCID 0000-0003-0301-8479
José M FragosoDepartamento de Biología Molecular, Instituto Nacional de Cardiología "Ignacio Chávez", Ciudad de México, Mexico.ORCID 0000-0003-3137-7815
Nallely Bueno-HernándezLaboratory for Proteomics and Metabolomics, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.
Sergio Islas-AndradeLaboratory for Proteomics and Metabolomics, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.
Guillermo Meléndez-MierLaboratory for Proteomics and Metabolomics, Research Division, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.ORCID 0000-0003-2992-6395
Galileo EscobedoLaboratory for Liver, Pancreas and Motility, Unit of Experimental Medicine, School of Medicine, National University of Mexico, General Hospital of Mexico "Dr. Eduardo Liceaga", 06726 Mexico City, Mexico.ORCID 0000-0002-9224-7400
Hospital General de México · MXHeidelberg University · DEAutonomous University of Tlaxcala · MXInstituto Nacional de Cardiología · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effect of metabolic syndrome on human monocyte subpopulations has not yet been studied. Our main goal was to examine monocyte subpopulations in metabolic syndrome patients, while also identifying the risk factors that could directly influence these cells. Eighty-six subjects were divided into metabolic syndrome patients and controls. Monocyte subpopulations were quantified by flow cytometry, and interleukin- (IL-) 1

Indexed as

Diet TherapyAdultCells, CulturedFemaleFlow CytometryHumansInterleukin-1betaLipopolysaccharidesLipoproteins, HDLMaleMetabolic SyndromeMiddle AgedMonocytesPrimary Cell CultureYoung AdultInterleukin-1betaLipopolysaccharidesLipoproteins, HDL

Identifiers

PMID29850624
PMCPMC5903324
OpenAlexW2795484905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.