Evidence map›Paper›PMID 29850546›Full record

ReviewBioMed research international2018

3D and 4D Bioprinting of the Myocardium: Current Approaches, Challenges, and Future Prospects.

Chin Siang Ong, Lucy Nam, Kingsfield Ong, Aravind Krishnan, Chen Yu Huang, Takuma Fukunishi, Narutoshi Hibino

Abstract readReview
In one paragraph

Review in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Stem Cell Therapy in Ischemic Heart Failure.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Recent advances in bioprinting technologies for engineering cardiac tissue.Materials science & engineering. C, Materials for biological applications · 2021
    Review
  19. Review
  20. Protein-Based 3D Biofabrication of Biomaterials.Bioengineering (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chin Siang OngDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Lucy NamDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Kingsfield OngDepartment of Cardiac, Thoracic and Vascular Surgery, National University Heart Centre, Singapore.
Aravind KrishnanDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Chen Yu HuangDivision of Cardiology, Johns Hopkins Hospital, Baltimore, MD, USA.
Takuma FukunishiDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Narutoshi HibinoDivision of Cardiac Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.ORCID 0000-0003-4551-9079

Funding

Training Program in Cellular and Molecular MedicineT32GM008752 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI RAO, RAJINI · 2000 to 2019
$11.7M
NIGMS NIH HHS T32 GM008752
6 · The paper itself

Abstract

3D and 4D bioprinting of the heart are exciting notions in the modern era. However, myocardial bioprinting has proven to be challenging. This review outlines the methods, materials, cell types, issues, challenges, and future prospects in myocardial bioprinting. Advances in 3D bioprinting technology have significantly improved the manufacturing process. While scaffolds have traditionally been utilized, 3D bioprinters, which do not require scaffolds, are increasingly being employed. Improved understanding of the cardiac cellular composition and multiple strategies to tackle the issues of vascularization and viability had led to progress in this field.

Indexed as

AnimalsBioprintingHumansMyocardiumNeovascularization, PhysiologicPrinting, Three-DimensionalTissue Scaffolds

Identifiers

PMID29850546
PMCPMC5937623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.