Evidence map›Paper›PMID 29850257›Full record

ReviewJournal of pathogens2018

Prevalence of Multidrug-Resistant Tuberculosis and Associated Factors in Ethiopia: A Systematic Review.

Solomon Weldegebreal Asgedom, Mebrahtu Teweldemedhin, Hailay Gebreyesus

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of pathogens, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
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  4. Pooled it
  5. Article
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  10. Variability in plasma rifampicin concentrations and role ofInfectious diseases (London, England) · 2024
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  11. Resistance to pyrazinamide inJournal of clinical tuberculosis and other mycobacterial diseases · 2024
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  12. Article
  13. Drug-Resistant Profiles and Genetic Diversity ofInfection and drug resistance · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Distribution and frequency of common mutations inJournal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
  18. Article
  19. The second national anti-tuberculosis drug resistance survey in Tanzania, 2017-2018.Tropical medicine & international health : TM & IH · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Solomon Weldegebreal AsgedomSchool of Pharmacy, College of Health Sciences, Mekelle University, Mek'ele, Ethiopia.ORCID 0000-0003-0804-3307
Mebrahtu TeweldemedhinUnit of Biomedical Science, School of Medicine, College of Health Sciences and Referral Hospital, Aksum University, Aksum, Ethiopia.
Hailay GebreyesusUnit of Health Education and Promotion, College of Health Sciences and Referral Hospital, Aksum University, Aksum, Ethiopia.
Aksum University · ETMekelle University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultidrug-resistant tuberculosis (MDR-TB) has continued to be a challenge for tuberculosis (TB) control globally. Ethiopia is one of the countries with high MDR-TB burden.

objectiveThe main purpose of this study was to determine the prevalence of MDR-TB and associated factors in Ethiopia.

methodsA systematic review of the literatures on prevalence of MDR-TB and associated factors was conducted in the country.

resultsIn our electronic search, 546 citations were depicted. Among the total 546 citations described, a total of 22 articles met eligibility criteria and were included in the review article. According to our review, the prevalence of MDR-TB ranged from 0 to 46.3%. The average mean rate of MDR-TB in Ethiopia was found to be 12.6 ± 15.9%. The overall prevalence of MDR-TB in all TB cases was estimated to be 1.4%. From a total of 3849 patients studied, 527 had MDR-TB. Previous exposure to antituberculosis treatment was the most commonly identified risk factor of MDR-TB in Ethiopia.

conclusionDespite relative decline in incidence of MDR-TB, the distribution and prevalence of MDR-TB continued to be a serious challenge for TB control in Ethiopia. Previous exposure to antituberculosis treatment was also the most common risk factor for MDR-TB. Therefore, strong TB and MDR-TB treatment along with tight introduction of follow-up strategies should be applied for better TB control.

Identifiers

PMID29850257
PMCPMC5903304
OpenAlexW2795509126

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.