Evidence map›Paper›PMID 29850142›Full record

ArticleJournal of thoracic disease2018

The diagnosis of coronary plaque stability by multi-slice computed tomography coronary angiography.

Feng-Xiang Song, Jun Zhou, Jian-Jun Zhou, Yu-Xin Shi, Meng-Su Zeng, Zhi-Yong Zhang, Peng Lv, Ruo-Fan Sheng

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Recent Trends in Artificial Intelligence-Assisted Coronary Atherosclerotic Plaque Characterization.International journal of environmental research and public health · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Feng-Xiang SongDepartment of Radiology, Shanghai Public Health Clinical Center, Shanghai 201508, China.
Jun ZhouDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Jian-Jun ZhouDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yu-Xin ShiDepartment of Radiology, Shanghai Public Health Clinical Center, Shanghai 201508, China.
Meng-Su ZengDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Zhi-Yong ZhangDepartment of Radiology, Shanghai Public Health Clinical Center, Shanghai 201508, China.
Peng LvDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Ruo-Fan ShengDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Shanghai Public Health Clinical Center · CNSun Yat-sen University · CNZhongshan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary computed tomographic angiography is a robust non-invasive method to assess coronary artery disease (CAD) and analyze coronary plaque stability, especially for the non-calcified plaques. The aim of this study was to investigate the differential characteristics between the unstable coronary plaques and the stable coronary plaques using multi-slice computed tomography (MSCT).

methodsSixty patients with coronary heart disease (37 unstable plaques and 31 stable plaques) were included. The napkin ring thickness, napkin-ring sign, plaque CT attenuation and degree of lumen stenosis were retrospectively analyzed. The diagnostic performances of MSCT were determined to predict the unstable plaques. The difference was statistically significant if P<0.05.

resultsThe napkin ring thickness of the unstable plaques was thinner than that of the stable plaques (P<0.05). The napkin-ring sign was more frequently observed in the unstable group (89.2%) than the stable group (22.6%, P<0.05). The average CT value of the unstable plaques (26.8±17.8 HU) was lower than that of the stable plaques (68.5±25.5 HU, P<0.05). The unstable plaques had more severe lumen stenosis or occlusion (70.3%) than the stable plaques (41.9%, P<0.05). The measurable napkin ring thickness of the plaques with a cutoff value of 0.8 mm and an accuracy of 89.5% was one independent factor to predict unstable plaques. The optimal combined threshold of the napkin-ring sign and/or the plaque CT value of 53 HU with an accuracy of 80.9% was to predict unstable plaques.

conclusionsThe optimal combined threshold of the napkin-ring sign and/or the plaque CT value ≤53 HU may be a good indicator to predict the unstable plaques in patients with CAD. The subgroup of measurable napkin ring thickness of the non-calcified plaques may also be an independent factor to predict the unstable plaques in patients with CAD.

Indexed as

atherosclerosiscomputed tomography angiographyCoronary artery disease (CAD)stable plaquesunstable plaques

Identifiers

PMID29850142
PMCPMC5949511
OpenAlexW2800086480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.