Evidence map›Paper›PMID 29850000›Full record

ArticleJournal of healthcare engineering2018

Potential of Electrospun Poly(3-hydroxybutyrate)/Collagen Blends for Tissue Engineering Applications.

Luca Salvatore, Vito Emanuele Carofiglio, Paolo Stufano, Valentina Bonfrate, Emanuela Calò, Stefania Scarlino, Paola Nitti, Domenico Centrone, Mariafrancesca Cascione, Stefano Leporatti and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of healthcare engineering, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

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  12. Bio-Based Electrospun Fibers for Wound Healing.Journal of functional biomaterials · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Luca SalvatoreDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Vito Emanuele CarofiglioDistretto Tecnologico High Tech DHITECH Scarl, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Paolo StufanoEggPlant Srl, Via Don Minzoni 27, 70044 Polignano a Mare, Italy.
Valentina BonfrateDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Emanuela CalòDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Stefania ScarlinoDistretto Tecnologico High Tech DHITECH Scarl, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Paola NittiDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Domenico CentroneEggPlant Srl, Via Don Minzoni 27, 70044 Polignano a Mare, Italy.
Mariafrancesca CascioneDepartment of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", Piazza Giulio Cesare 11, 70124 Bari, Italy.
Stefano LeporattiInstitute of Nanotechnology of the National Research Council (CNR NANOTEC), CNR, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Alessandro SanninoDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.
Christian DemitriDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.ORCID 0000-0002-1145-6674
Marta MadaghieleDepartment of Engineering for Innovation, University of Salento, Campus Ecotekne, Via per Monteroni, 73100 Lecce, Italy.ORCID 0000-0003-3039-9107
University of Salento · ITIstituto di Nanotecnologia · ITUniversity of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, tunable nonwoven mats based on poly(3-hydroxybutyrate) (PHB) and type I collagen (Coll) were successfully produced by electrospinning. The PHB/Coll weight ratio (fixed at 100/0, 70/30, and 50/50, resp.) was found to control the morphological, thermal, mechanical, and degradation properties of the mats. Increasing collagen amounts led to larger diameters of the fibers (in the approximate range 600-900 nm), while delaying their thermal decomposition (from 245°C to 262°C). Collagen also accelerated the hydrolytic degradation of the mats upon incubation in aqueous medium at 37°C for 23 days (with final weight losses of 1%, 15%, and 23% for 100/0, 70/30, and 50/50 samples, resp.), as a result of increased mat wettability and reduced PHB crystallinity. Interestingly, 70/30 meshes were the ones displaying the lowest stiffness (~116 MPa;

Indexed as

Biocompatible Materials3-Hydroxybutyric AcidAnimalsCell ProliferationCell SurvivalCollagenCollagen Type IHot TemperatureHydrolysisHydroxybutyratesMiceNIH 3T3 CellsPolyestersPolyhydroxybutyratesPolymersPorosity3-Hydroxybutyric AcidBiocompatible MaterialsCollagenCollagen Type IHydroxybutyratesPHB protein, humanpoly-beta-hydroxybutyratePolyestersPolyhydroxybutyratesPolymersPowdersProhibitins

Identifiers

PMID29850000
PMCPMC5933042
OpenAlexW2802993494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.