Evidence map›Paper›PMID 29849983›Full record

ArticleAvicenna journal of medical biotechnology

Ectopic Expression of Human

Maryam Khaleghizadeh, Mohammad Mahdi Forghanifard, Abolfazl Rad, Moein Farshchian, Zahra Hejazi, Mehran Gholamin, Bahram Memar, Mohammad Reza Abbaszadegan

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Avicenna journal of medical biotechnology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Maryam KhaleghizadehDepartment of Microbiology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Mohammad Mahdi ForghanifardDepartment of Biology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Abolfazl RadCellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Moein FarshchianHuman Genetic Division, Immunology Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Zahra HejaziDepartment of Microbiology, Damghan Branch, Islamic Azad University, Damghan, Iran.
Mehran GholaminHuman Genetic Division, Immunology Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Bahram MemarDepartment of Pathology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza AbbaszadeganHuman Genetic Division, Immunology Research Center, Avicenna Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Islamic Azad University, Damghan Branch · IRMashhad University of Medical Sciences · IRSabzevar University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer/Testis Antigens (CTAs) are a sub-group of tumor-associated antigens which are expressed normally in germ line cells and trophoblast, and aberrantly in a variety of malignancies. One of the most important CTAs is Developmental Pluripotency Associated-2(DPPA2) with unknown biological function. Considering the importance of

methodsIn this study, the coding sequence of

resultsAccording to the critical characteristics of retroviral expression system such as stable and long time expression of interested gene and also being safe due to deletion of retroviral pathogenic genes, this system was used to induce expression of

conclusionSuch strategies can be used to produce high levels of desired protein in target cells as a therapeutic target. The produced recombinant cells may present a valuable platform to analyze the effect of

Indexed as

CarcinogenesisEsophageal squamous cell carcinomaGerm cellsTestis

Identifiers

PMID29849983
PMCPMC5960063
OpenAlexW2807018918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.