Evidence map›Paper›PMID 29849944›Full record

ArticleOncotarget2018

MicroRNA expression in pre-treatment plasma of patients with benign breast diseases and breast cancer.

Mirelle Lagendijk, Sepideh Sadaatmand, Linetta B Koppert, Madeleine M A Tilanus-Linthorst, Vanja de Weerd, Raquel Ramírez-Moreno, Marcel Smid, Anieta M Sieuwerts, John W M Martens

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mirelle LagendijkDepartment of Surgical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Sepideh SadaatmandDepartment of Surgical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Linetta B KoppertDepartment of Surgical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Madeleine M A Tilanus-LinthorstDepartment of Surgical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Vanja de WeerdDepartment of Medical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Raquel Ramírez-MorenoDepartment of Medical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Marcel SmidDepartment of Medical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Anieta M SieuwertsDepartment of Medical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
John W M MartensDepartment of Medical Oncology, Erasmus MC Cancer Institute, EA 3075, Rotterdam, The Netherlands.
Erasmus MC Cancer Institute · NLCancer Genomics Centre · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicroRNAs (miRs) are small RNA molecules, influencing messenger RNA (mRNA) expression and translation, and are readily detectable in blood. Some have been reported as potential breast cancer biomarkers. This study aimed to identify and validate miRs indicative of breast cancer.

resultsBased on the discovery and literature, 18 potentially informative miRs were quantified in the validation cohort. Irrespective of patient and tumour characteristics,

methodsPre-treatment plasma samples were collected of patients with benign breast disease and breast cancer and divided over a discovery (

conclusionsPlasma microRNA levels differed between patients with and without breast cancer, between benign disease from wildtype and

Indexed as

BRCA1-mutation carriersbreast cancermicro arraymicroRNART-qPCR

Identifiers

PMID29849944
PMCPMC5966243
OpenAlexW2802374229

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.