Evidence map›Paper›PMID 29849926›Full record

ArticleOxidative medicine and cellular longevity2018

Hepatoprotective Activity of Vitamin E and Metallothionein in Cadmium-Induced Liver Injury in

Yajiao Duan, Jing Duan, Yang Feng, Xiaoli Huang, Wei Fan, Kaiyu Wang, Ping Ouyang, Yongqiang Deng, Zongjun Du, Defang Chen and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Curative Potential of Substances with Bioactive Properties to Alleviate Cd Toxicity: A Review.International journal of environmental research and public health · 2022
    Review
  6. The role of well-known antioxidant vitamins in the prevention of cadmium-induced toxicity.International journal of occupational medicine and environmental health · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Efficient Removal of Cd(II) Using SiOInternational journal of environmental research and public health · 2020
    Article
  12. Protective effects of vitamin E on cadmium-induced apoptosis in rat testes.Naunyn-Schmiedeberg's archives of pharmacology · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Yajiao DuanDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Jing DuanDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Yang FengDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.ORCID 0000-0001-9089-6899
Xiaoli HuangDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.ORCID 0000-0001-6570-4779
Wei FanNeijiang City Academy of Agricultural Sciences, Neijiang, Sichuan 641000, China.
Kaiyu WangCollege of Animal Science and Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.ORCID 0000-0003-0229-9096
Ping OuyangCollege of Animal Science and Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Yongqiang DengAnimal Disease Prevention and Control Center of Sichuan Province, Chengdu, Sichuan 610000, China.
Zongjun DuDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Defang ChenDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Yi GengCollege of Animal Science and Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Shiyong YangDepartment of Aquaculture, Sichuan Agricultural University, Wenjiang, Sichuan 611130, China.
Sichuan Agricultural University · CNNeijiang Normal University · CNSichuan Center for Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an environmental and industrial pollutant, cadmium (Cd) can cause a broad spectrum of toxicological effects. Multiple organs, especially the liver, are considerably affected by Cd in both humans and animals. We investigated the protective effects of metallothionein (MT) and vitamin E (VE) supplementation on Cd-induced apoptosis in the grass carp (

Indexed as

AnimalsApoptosisbcl-2-Associated X ProteinCadmium ChlorideCarpsCaspase 3Endoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsLipid PeroxidationLiverMalondialdehydeMetallothioneinProtective AgentsProto-Oncogene Proteins c-bcl-2Vitamin Ebcl-2-Associated X ProteinCadmium ChlorideCaspase 3Endoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsMalondialdehydeMetallothioneinProtective AgentsProto-Oncogene Proteins c-bcl-2Vitamin E

Identifiers

PMID29849926
PMCPMC5924983
OpenAlexW2796668272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.