Evidence map›Paper›PMID 29849920›Full record

ArticleOxidative medicine and cellular longevity2018

Longevity-Related Gene Transcriptomic Signature in Glioblastoma Multiforme.

Manal S Fawzy, Dahlia I Badran, Essam Al Ageeli, Saeed Awad M Al-Qahtani, Saleh Ali Alghamdi, Ghada M Helal, Eman A Toraih

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. HighCancers · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Manal S FawzyDepartment of Medical Biochemistry, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0003-1252-8403
Dahlia I BadranDepartment of Medical Biochemistry, Faculty of Medicine, Suez Canal University, Ismailia 41522, Egypt.ORCID 0000-0002-8234-2674
Essam Al AgeeliDepartment of Clinical Biochemistry (Medical Genetics), Faculty of Medicine, Jazan University, Jazan, Saudi Arabia.
Saeed Awad M Al-QahtaniDepartment of Physiology, Faculty of Medicine, Taibah University, Almadinah Almunawwarah, Saudi Arabia.
Saleh Ali AlghamdiMedical Genetics, Clinical Laboratory Department, College of Applied Medical Sciences, Taif University, Taif, Saudi Arabia.
Ghada M HelalDepartment of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Eman A ToraihCenter of excellence in Molecular and Cellular Medicine, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID 0000-0001-9267-3787
Suez Canal University · EGJazan University · SAMansoura University · EGTaibah University · SATaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) (grade IV astrocytoma) has been assumed to be the most fatal type of glioma with low survival and high recurrence rates, even after prompt surgical removal and aggressive courses of treatment. Transcriptional reprogramming to stem cell-like state could explain some of the deregulated molecular signatures in GBM disease. The present study aimed to quantify the expression profiling of longevity-related transcriptional factors

Indexed as

TranscriptomeAdultArea Under CurveBrain NeoplasmsDisease-Free SurvivalDown-RegulationFemaleGlioblastomaHumansKaplan-Meier EstimateLinear ModelsLongevityMaleMiddle AgedNanog Homeobox ProteinNeoplasm StagingNanog Homeobox ProteinOctamer Transcription Factor-3POU5F1 protein, humanSOX2 protein, humanSOXB1 Transcription Factors

Identifiers

PMID29849920
PMCPMC5914091
OpenAlexW2792971866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.