Evidence map›Paper›PMID 29849915›Full record

ArticleOxidative medicine and cellular longevity2018

Hippocampal Dysfunction Provoked by Mercury Chloride Exposure: Evaluation of Cognitive Impairment, Oxidative Stress, Tissue Injury and Nature of Cell Death.

Walessa Alana Bragança Aragão, Francisco Bruno Teixeira, Nathalia Carolina Fernandes Fagundes, Rafael Monteiro Fernandes, Luanna Melo Pereira Fernandes, Márcia Cristina Freitas da Silva, Lilian Lund Amado, Fernanda Espírito Santo Sagica, Edivaldo Herculano Correa Oliveira, Maria Elena Crespo-Lopez and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Subchronic effects of HgClFrontiers in toxicology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Walessa Alana Bragança AragãoLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Francisco Bruno TeixeiraLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Nathalia Carolina Fernandes FagundesLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Rafael Monteiro FernandesLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Luanna Melo Pereira FernandesLaboratory of Pharmacology of Inflammation and Behavior, Institute of Health Sciences, Federal University of Pará, Belém, PA, Brazil.
Márcia Cristina Freitas da SilvaLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Lilian Lund AmadoLaboratory of Ecotoxicology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.
Fernanda Espírito Santo SagicaLaboratory of Tissue Culture and Cytogenetics, Evandro Chagas Institute, Ananindeua, PA, Brazil.
Edivaldo Herculano Correa OliveiraLaboratory of Tissue Culture and Cytogenetics, Evandro Chagas Institute, Ananindeua, PA, Brazil.
Maria Elena Crespo-LopezLaboratory of Molecular Pharmacology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.ORCID 0000-0002-1335-6853
Cristiane Socorro Ferraz MaiaLaboratory of Pharmacology of Inflammation and Behavior, Institute of Health Sciences, Federal University of Pará, Belém, PA, Brazil.ORCID 0000-0003-4493-7375
Rafael Rodrigues LimaLaboratory of Functional and Structural Biology, Institute of Biological Sciences, Federal University of Pará, Belém, PA, Brazil.ORCID 0000-0003-1486-4013
Universidade Federal do Pará · BRInstituto Evandro Chagas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mercury (Hg) is a highly toxic metal, which can be found in its inorganic form in the environment. This form presents lower liposolubility and lower absorption in the body. In order to elucidate the possible toxicity of inorganic Hg in the hippocampus, we investigated the potential of low doses of mercury chloride (HgCl

Indexed as

AnimalsAntioxidantsApoptosisAstrocytesBehavior, AnimalBody WeightBrainHippocampusMaleMercuric ChlorideNeuronsOxidative StressRatsRats, WistarReactive Oxygen SpeciesAntioxidantsMercuric ChlorideReactive Oxygen Species

Identifiers

PMID29849915
PMCPMC5914100
OpenAlexW2796717838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.