Evidence map›Paper›PMID 29849896›Full record

ArticleOxidative medicine and cellular longevity2018

Aerobic Training Prevents Heatstrokes in Calsequestrin-1 Knockout Mice by Reducing Oxidative Stress.

Flávia Alessandra Guarnier, Antonio Michelucci, Matteo Serano, Laura Pietrangelo, Claudia Pecorai, Simona Boncompagni, Feliciano Protasi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Exercise sustains the hallmarks of health.Journal of sport and health science · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Ablation of Calsequestrin-1, CaFrontiers in physiology · 2022
    Review
  8. Calsequestrin, a key protein in striated muscle health and disease.Journal of muscle research and cell motility · 2021
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Flávia Alessandra GuarnierCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.ORCID 0000-0001-9302-878X
Antonio MichelucciCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.
Matteo SeranoCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.
Laura PietrangeloCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.
Claudia PecoraiCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.
Simona BoncompagniCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.ORCID 0000-0001-5308-5069
Feliciano ProtasiCenter for Research on Ageing and Translational Medicine (CeSI-MeT), University G. d'Annunzio, 66100 Chieti, Italy.ORCID 0000-0002-0213-7591
University of Chieti-Pescara · ITUniversidade Estadual de Londrina · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calsequestrin-1 knockout (CASQ1-null) mice suffer lethal episodes when exposed to strenuous exercise and environmental heat, crises known as exertional/environmental heatstroke (EHS). We previously demonstrated that administration of exogenous antioxidants (

Indexed as

AnimalsCalcium-Binding ProteinsCalsequestrinGene Knockout TechniquesHeat StrokeMaleMiceMice, KnockoutOxidative StressPhysical Conditioning, AnimalCalcium-Binding ProteinsCalsequestrinCasq1 protein, mouse

Identifiers

PMID29849896
PMCPMC5903204
OpenAlexW2795465672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.