Evidence map›Paper›PMID 29849884›Full record

ArticleOxidative medicine and cellular longevity2018

DUOX1 Silencing in Mammary Cell Alters the Response to Genotoxic Stress.

Rodrigo S Fortunato, Luciana R Gomes, Veridiana Munford, Carolina Fittipaldi Pessoa, Annabel Quinet, Fabio Hecht, Gustavo S Kajitani, Cristiane Bedran Milito, Denise P Carvalho, Carlos Frederico Martins Menck

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. NOX Family: Regulators of Reactive Oxygen Species Balance in Tumor Cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
  3. Article
  4. Article
  5. DUOX1 in mammalian disease pathophysiology.Journal of molecular medicine (Berlin, Germany) · 2021
    Review
  6. Article
  7. Article
  8. Inhibiting the Activity of NADPH Oxidase in Cancer.Antioxidants & redox signaling · 2020
    Article
  9. The role of dual oxidases in physiology and cancer.Genetics and molecular biology · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Rodrigo S FortunatoLaboratório de Radiobiologia Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0003-3497-8173
Luciana R GomesLaboratório de Reparo de DNA, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Veridiana MunfordLaboratório de Reparo de DNA, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Carolina Fittipaldi PessoaLaboratório de Radiobiologia Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Annabel QuinetLaboratório de Reparo de DNA, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Fabio HechtLaboratório de Radiobiologia Molecular, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Gustavo S KajitaniLaboratório de Reparo de DNA, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.
Cristiane Bedran MilitoDepartamento de Patologia, Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Denise P CarvalhoLaboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.ORCID 0000-0001-6933-6424
Carlos Frederico Martins MenckLaboratório de Reparo de DNA, Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID 0000-0003-1941-0694
Universidade de São Paulo · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DUOX1 is an H

Indexed as

Breast NeoplasmsCell Line, TumorCell MovementCell ProliferationDNA DamageDown-RegulationDoxorubicinDual OxidasesFemaleGene Knockdown TechniquesGene SilencingHumansHydrogen PeroxideInterleukin-6Interleukin-8Tumor Cells, CulturedDoxorubicinDual OxidasesDUOX1 protein, humanHydrogen PeroxideIL6 protein, humanInterleukin-6Interleukin-8

Identifiers

PMID29849884
PMCPMC5933011
OpenAlexW2801944767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.