Evidence map›Paper›PMID 29849876›Full record

ArticleOxidative medicine and cellular longevity2018

Work Intensity, Low-Grade Inflammation, and Oxidative Status: A Comparison between Office and Slaughterhouse Workers.

Sieglinde Zelzer, Franz Tatzber, Markus Herrmann, Willibald Wonisch, Stefan Rinnerhofer, Michael Kundi, Barbara Obermayer-Pietsch, Tobias Niedrist, Gerhard Cvirn, Georg Wultsch and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Observational
  3. Assessment of ventilatory functions and associated inflammatory markers among workers in slaughterhouses.International archives of occupational and environmental health · 2024
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  16. Oxidative Stress Indexes for Diagnosis of Health or Disease in Humans.Oxidative medicine and cellular longevity · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sieglinde ZelzerClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria.ORCID 0000-0002-8653-0779
Franz TatzberCenter of Molecular Medicine, Institute of Pathophysiology and Immunology, Medical University of Graz, Heinrichstrasse 31a, 8010 Graz, Austria.
Markus HerrmannClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria.
Willibald WonischInstitute of Physiological Chemistry, Center for Physiological Medicine, Medical University of Graz, Stiftingtalstrasse 6 M1/D/3, 8036 Graz, Austria.ORCID 0000-0001-7171-9539
Stefan RinnerhoferExercise Physiology, Training and Training Therapy Research Group, Institute of Sports Science, University of Graz, Mozartgasse 14, 8010 Graz, Austria.
Michael KundiDepartment of Environmental Health, Center for Public Health, Medical University Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria.
Barbara Obermayer-PietschDivision of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.
Tobias NiedristClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria.
Gerhard CvirnInstitute of Physiological Chemistry, Center for Physiological Medicine, Medical University of Graz, Stiftingtalstrasse 6 M1/D/3, 8036 Graz, Austria.
Georg WultschArbeitsmedizinisches Institut, Graz, Herrgottwiesgasse 149, 8055 Graz, Austria.
Harald ManggeClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Auenbruggerplatz 29, 8036 Graz, Austria.
Medical University of Graz · ATMedical University of Vienna · ATUniversity of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited knowledge exists about the impact of physical workload on oxidative stress in different occupational categories. Thus, we aimed to investigate the oxidative and inflammatory status in employees with different physical workloads. We enrolled a total of 79 male subjects, 27 office workers (mean age 38.8 ± 9.1 years) and 52 heavy workers, in a slaughterhouse (mean age 40.8 ± 8.2 years). Fasting blood was drawn from an antecubital vein in the morning of the midweek before an 8-hour or 12-hour work shift. The antioxidative capacity was assessed measuring total antioxidant capacity (TAC), uric acid, total polyphenols (PPm), and endogenous peroxidase activity (EPA). Total peroxides (TOC), malondialdehyde (MDA), and myeloperoxidase (MPO) were analyzed as prooxidative biomarkers, and an oxidative stress index (OSI) was calculated. In addition, hsCRP, interleukin-6 (IL-6), MDA-LDL IgM antibodies, galectin-3, adrenocorticotropic hormone (ACTH), and the brain-derived neurotrophic factor (BDNF) were measured as biomarkers of chronic systemic inflammation and emotional stress. TOC (

Indexed as

AdolescentAdultAgedFemaleHealth OccupationsHumansInflammationMaleMiddle AgedOxidative StressWorkloadYoung Adult

Identifiers

PMID29849876
PMCPMC5932461
OpenAlexW2801142523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.