Evidence map›Paper›PMID 29849868›Full record

ArticleOxidative medicine and cellular longevity2018

Anti-Inflammatory Activity of Marine Ovothiol A in an

Immacolata Castellano, Pamela Di Tomo, Natalia Di Pietro, Domitilla Mandatori, Caterina Pipino, Gloria Formoso, Alessandra Napolitano, Anna Palumbo, Assunta Pandolfi

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 44 citations in OpenAlex.

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  17. Kinetic Studies of Antioxidant Properties of Ovothiol A.Antioxidants (Basel, Switzerland) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Immacolata CastellanoDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Napoli, Italy.
Pamela Di TomoDepartment of Medicine and Aging Sciences, "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.
Natalia Di PietroDepartment of Medicine and Aging Sciences, "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.
Domitilla MandatoriDepartment of Medicine and Aging Sciences, "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.
Caterina PipinoCentro Scienze dell'Invecchiamento-Medicina Traslazionale (CeSI-MeT), "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.ORCID 0000-0002-4350-8686
Gloria FormosoDepartment of Medicine and Aging Sciences, "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.
Alessandra NapolitanoDepartment of Chemical Sciences, University of Naples Federico II, Naples, Italy.ORCID 0000-0003-0507-5370
Anna PalumboDepartment of Biology and Evolution of Marine Organisms, Stazione Zoologica Anton Dohrn, Napoli, Italy.ORCID 0000-0002-5972-5589
Assunta PandolfiCentro Scienze dell'Invecchiamento-Medicina Traslazionale (CeSI-MeT), "G. d'Annunzio" University Chieti-Pescara, Chieti, Italy.ORCID 0000-0003-4135-7631
University of Chieti-Pescara · ITStazione Zoologica Anton Dohrn · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic hyperglycemia is associated with oxidative stress and vascular inflammation, both leading to endothelial dysfunction and cardiovascular disease that can be weakened by antioxidant/anti-inflammatory molecules in both healthy and diabetic subjects. Among natural molecules, ovothiol A, produced in sea urchin eggs to protect eggs/embryos from the oxidative burst at fertilization and during development, has been receiving increasing interest for its use as an antioxidant. Here, we evaluated the potential antioxidative/anti-inflammatory effect of purified ovothiol A in an

Indexed as

AdultAnimalsAnti-Inflammatory AgentsDiabetes, GestationalEndothelial CellsFemaleFishesHumansHyperglycemiaMethylhistidinesPregnancyAnti-Inflammatory AgentsMethylhistidinesovothiol A

Identifiers

PMID29849868
PMCPMC5932987
OpenAlexW2802568277

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.