Evidence map›Paper›PMID 29849799›Full record

ArticleOncology letters2018

A rapidly growing human papillomavirus-positive oral tongue squamous cell carcinoma in a 21-year old female: A case report.

Ebenezer O Appah, Billy Ray Ballard, Michael G Izban, Cassandra Jolin, Philip E Lammers, Dwight D Parrish, Dana R Marshall

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. NovelFrontiers in medicine · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ebenezer O AppahDepartment of Internal Medicine, Meharry Medical College, Nashville, TN 37208, USA.
Billy Ray BallardDepartment of Pathology, Anatomy and Cell Biology, Meharry Medical College, Nashville, TN 37208, USA.
Michael G IzbanDepartment of Pathology, Anatomy and Cell Biology, Meharry Medical College, Nashville, TN 37208, USA.
Cassandra JolinDepartment of Family and Community Medicine, Meharry Medical College, Nashville, TN 37208, USA.
Philip E LammersDepartment of Internal Medicine, Meharry Medical College, Nashville, TN 37208, USA.
Dwight D ParrishDepartment of Pathology, Anatomy and Cell Biology, Meharry Medical College, Nashville, TN 37208, USA.
Dana R MarshallDepartment of Pathology, Anatomy and Cell Biology, Meharry Medical College, Nashville, TN 37208, USA.
Meharry Medical College · US

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
Determining high risk HPV status in the underservedR21CA199632 · NCI · MEHARRY MEDICAL COLLEGE · PI MARSHALL, DANA ROBIN · 2015 to 2016
$348k
NCI NIH HHS K12 CA090625NCI NIH HHS R21 CA199632
6 · The paper itself

Abstract

Oral tongue squamous cell carcinoma (OTSCC) has a median age at diagnosis of 62 years. The incidence of OTSCC in young adults has been increasing, and the reason is unclear. The present study describes a case, and molecular analysis, of OTSCC in a 21-year-old female. Clinical and pathological information were collected from medical records. Formalin-fixed paraffin-embedded biopsy tissue from the patient was reassessed using standard hematoxylin & eosin staining, and immunohistochemistry was used to assess the expression of cellular p16, MutL homolog (MLH)1, MLH2, MutS homolog 6 (MSH6) and PMS1 homolog 2 (PMS2). The human papilloma virus (HPV) genome was detected by PCR analysis of the extracted DNA. The young age of the patient with OTSCC was unusual. The original pathology report indicated

Indexed as

anterior tonguehuman papillomavirusmobile tongueoral tonguesquamous cell carcinomatongue cancer

Identifiers

PMID29849799
PMCPMC5962839
OpenAlexW2789522559

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.