Evidence map›Paper›PMID 29849713›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Immunomodulatory Effects of Kuseonwangdogo-Based Mixed Herbal Formula Extracts on a Cyclophosphamide-Induced Immunosuppression Mouse Model.

Joo Wan Kim, Jae-Suk Choi, Du Jin Seol, Jai Jun Choung, Sae Kwang Ku

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Extraction and Identification of Polysaccharide fromInternational journal of molecular sciences · 2024
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  3. Article
  4. A Water-Soluble Polysaccharide from the Fibrous Root ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Article
  6. Acupuncture Inhibits Morphine Induced-Immune Suppress via Antioxidant System.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joo Wan KimAribio Co. Ltd., No. 2-301, Pangyo Seven Venture Valley, 15 Pangyoro 229-gil, Bundang-gu, Sungnam, Gyeonggi-do 13487, Republic of Korea.
Jae-Suk ChoiDivision of Bioindustry, College of Medical and Life Sciences, Silla University, 140 Baegyang-daero 700 Beon-gil, Sasang-gu, Busan 46958, Republic of Korea.ORCID 0000-0002-8151-6054
Du Jin SeolAribio Co. Ltd., No. 2-301, Pangyo Seven Venture Valley, 15 Pangyoro 229-gil, Bundang-gu, Sungnam, Gyeonggi-do 13487, Republic of Korea.
Jai Jun ChoungAribio Co. Ltd., No. 2-301, Pangyo Seven Venture Valley, 15 Pangyoro 229-gil, Bundang-gu, Sungnam, Gyeonggi-do 13487, Republic of Korea.
Sae Kwang KuDepartment of Anatomy and Histology, College of Korean Medicine, Daegu Haany University, Hanuidae-ro, Gyeongsan-si, Gyeongsangbuk-do 38610, Republic of Korea.ORCID 0000-0003-1269-3804
Daegu Haany University · KRSilla University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimKuseonwangdogo is a traditional Korean immunomodulatory polyherbal prescription. However, there are no systemic findings on its complex immunomodulatory effects on

methodsIn total, 60 male 6-week-old ICR mice (10 mice/group) were selected based on body weight 24 h after the second CPA treatment and used in this experiment. Twelve hours after the end of the last (fourth) oral administration of MHFe, the animals were sacrificed.

resultsFollowing CPA treatment, a noticeable decrease in the body, thymus, spleen, and submandibular lymph node (LN) weights; white blood cell, red blood cell, platelet number, hemoglobin, and hematocrit concentrations; serum interferon-

conclusionMHFe can be a promising, potent immunomodulatory therapeutic agent for various immune disorders.

Identifiers

PMID29849713
PMCPMC5911329
OpenAlexW2795646289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.