Evidence map›Paper›PMID 29849703›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Extraction of Polysaccharide from

Bingyue Wang, Qian Liu, Yinghong Huang, Yueling Yuan, Qianqian Ma, Manling Du, Tiange Cai, Yu Cai

Open access · hybridAbstract read
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Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Bingyue WangCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Qian LiuGuangzhou Jiayuan Pharmaceutical Technology Co., Ltd., Guangzhou 510632, China.
Yinghong HuangGuangzhou Guoyu Pharmaceutical Technology Co., Ltd., Guangzhou 510632, China.
Yueling YuanCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Qianqian MaCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Manling DuCollege of Pharmacy, Jinan University, Guangzhou 510632, China.
Tiange CaiCollege of Life Sciences, Liaoning University, Shenyang 110000, China.ORCID 0000-0001-9228-2372
Yu CaiCollege of Pharmacy, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-3833-5589
Jinan University · CNLiaoning University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolysaccharide of

objectiveThis study aims to identify an extraction process for high-purity polysaccharide in

methodsFour kinds of extraction methods-hot-water extraction, alkali extraction, ultrasonic-assisted extraction, and freeze-thaw extraction-were compared to find the optimal one, which was further optimized by response surface methodology. PSP was obtained after the crude PSP was deproteinized and depigmented. The antiaging effects of PSP were preliminarily evaluated through in vitro cell experiments.

resultsThe alkali extraction method was determined as the optimal method, with the optimized extraction process consisting of a solid-liquid ratio of 1 : 50, a pH value of 10.25, a temperature of 89.24°C, and a time of 9.99 h. The final PSP contained 71.65% of polysaccharide and 8.54% of protein. At a concentration of 50

conclusionAn extraction method for high-purity PSP with a high extraction rate was established, and in vitro results suggest antioxidation and antiaging activities.

Identifiers

PMID29849703
PMCPMC5925140
OpenAlexW2796743836

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.