ArticleInternational journal of pediatrics2018
Evaluation of Clinical and Immunological Characteristics of Children with Common Variable Immunodeficiency.
Article in International journal of pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Diagnostic Yield of Next Generation Sequencing in Genetically Undiagnosed Patients with Primary Immunodeficiencies: a Systematic Review.Journal of clinical immunology · 2019Pooled it
- Clinical and Laboratory Features of Pediatric Agammaglobulinemia: A Comparative Analysis of Classical, Common Variable Immunodeficiency, and Syndromic Forms.Indian pediatrics · 2026Article
- The Burden of Non-Infectious Organ-Specific Immunopathology in Pediatric Common Variable Immunodeficiency.International journal of molecular sciences · 2025Review
- Diagnostic tests for primary immunodeficiency disorders: Classic and genetic testing.Allergy and asthma proceedings · 2024Review
- Review
- Immune Dysregulation in Pediatric Common Variable Immunodeficiency: Implications for the Diagnostic Approach.Frontiers in pediatrics · 2022Article
- Primary Antibody Deficiencies With Pulmonary Complications: A Single-Center Experience.Cureus · 2022Article
- Autoimmune Cytopenias in Common Variable Immunodeficiency Are a Diagnostic and Therapeutic Conundrum: An Update.Frontiers in immunology · 2022Review
- Common variable immunodeficiency: different faces of the same disease.Postepy dermatologii i alergologii · 2021Article
- Evaluation of pulmonary findings in patients with humoral immunodeficiency.Turk pediatri arsivi · 2020Article
- Whole exome sequencing identifies compound heterozygous variants ofSAGE open medicine · 2020Article
- Recurrent episodes of pneumonia in a toddler: Don't forget chronic granulomatous disease.Journal of family medicine and primary care · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCommon variable immunodeficiency (CVID) is a primary immunodeficiency disorder (PID) that typically presents with hypogammaglobulinemia and impaired antibody production.
objectivesThis study aimed to promote the awareness of CVID, whose clinical spectrum is quite broad.
methodsThe demographic, clinical, and laboratory characteristics of 12 children (seven males and five females) with CVID were analyzed retrospectively. The patients were diagnosed using the diagnostic criteria of the European Society for Primary Immunodeficiencies.
resultsThe median disease onset age was 7.2 ± 4.1 years, and the mean diagnosis age was 11.6 ± 3.7 years. The diagnosis delay was 4.3 ± 2.6 years, and the parental consanguinity rate was 75%. Most patients presented with recurrent infections, including upper respiratory tract infections (
conclusionCVID is a heterogeneous disease, so the diagnosis is frequently delayed. In the CVID patients with pulmonary complications, relationships were seen with the diagnosis delay, symptom onset age, and lung infection prevalence. Overall, the early diagnosis and treatment of PIDs can preclude life-threatening complications.
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Registered trials
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