ArticleInternational journal of dentistry2018
SNP Analysis of Caries and Initial Caries in Finnish Adolescents.
Article in International journal of dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- [Polymorphisms associated with dental caries in pediatric populations: a systematic review].Revista medica del Instituto Mexicano del Seguro Social · 2023Pooled it
- The Role of Oxidative Stress-Related Gene Polymorphisms (Medicina (Kaunas, Lithuania) · 2025Article
- Article
- The association between genetic polymorphisms in matrix metalloproteinases and caries experience.Clinical oral investigations · 2021Article
- The relationship between molar incisor hypomineralization, dental caries, socioeconomic factors, and polymorphisms in the vitamin D receptor gene: a population-based study.Clinical oral investigations · 2020Article
- Matrix metalloproteinases gene variants and dental caries in Czech children.BMC oral health · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental caries is the most common infection in the world and is influenced by genetic and environmental factors. Environmental factors are largely known, but the role of genetic factors is quite unknown. The aim was to investigate the genetic background of caries in Finnish adolescents. MATERIALS AND
methodsThis study was carried out at the Kotka Health Center in Eastern Finland. 94 participants aged 15-17 years gave approval for the saliva and DNA analyses. However, one was excluded in DNA analysis; thus, the overall number of participants in analysis was 93. Caries status was recorded clinically and from bite-wing X-rays to all 94 participants. Genomic DNA was extracted by genomic QIAamp® DNA Blood Mini Kit and genotyped for polymorphisms. The results were analyzed using additive and logistic regression models.
resultsNo significant associations between caries and the genes studied were found. However, SNPs in
conclusionThe present study could not demonstrate statistically significant associations between caries and the genes studied. Further studies with larger populations are needed.
Identifiers
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Registered trials
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