ReviewJournal of oncology2018
Multiple Myeloma of the Central Nervous System: 13 Cases and Review of the Literature.
Review in Journal of oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 48 citations in OpenAlex.
- Unusual CNS relapse of plasma cell leukemia manifesting as multiple extra-axial brain lesions: A case report with literature review.Radiology case reports · 2026Article
- Clinical Characteristics, Treatment Patterns, and Prognosis of Central Nervous System Involvement in Multiple Myeloma: A Multicenter Retrospective Study From China.Cancer medicine · 2026Article
- CNS Involvement of Multiple Myeloma-A Case Series and Narrative Literature Review.Journal of clinical medicine · 2026Article
- Suspected central nervous system involvement in multiple myeloma on MRI.Radiology case reports · 2026Article
- Bispecific antibody therapy in CNS myeloma: Early evidence from a multicentre cohort.British journal of haematology · 2025Article
- Central nervous system myeloma: Pathogenesis, diagnostic challenges, and practical management strategies.HemaSphere · 2025Review
- Article
- Outcome of Patients With Central Nervous System Multiple Myeloma (CNS-MM) Treated With CNS-Directed Radiation Therapy.Clinical lymphoma, myeloma & leukemia · 2025Article
- Spinal intradural lesion as manifestation of multiple myeloma: Illustrative case and systematic review of literature.Surgical neurology international · 2025Article
- Isolated relapse of multiple myeloma in the central nervous system post autologous hematopoietic stem cell transplantation: a case report and literature review.Frontiers in oncology · 2025Article
- Isolated Progression of Multiple Myeloma into the Extramedullary Plasmacytoma of Dura Mater: A Case Report and Review of the Literature.Biomedicines · 2023Article
- Encephalitis associated with a monoclonal protein band present in blood, urine and cerebrospinal fluid.Practical laboratory medicine · 2023Article
- Case reports: Central nervous system involvement in patients with newly diagnosed multiple myeloma.Frontiers in neurology · 2023Article
- Successful eradication of central nervous system infiltration of primary plasma cell leukemia by temozolomide.Annals of hematology · 2022Article
- Case report: Relapsed/refractory extranodal natural killer/T-cell lymphoma nasal type with extensive central nervous system involvement.Pathology oncology research : POR · 2022Article
- Multiple Myeloma with CNS Involvement in the Form of Leptomeningeal Carcinomatosis Presenting as Vitamin B12 Deficiency.Journal of community hospital internal medicine perspectives · 2022Article
- Central Nervous System Myeloma and Unusual Extramedullary Localizations: Real Life Practical Guidance.Frontiers in oncology · 2022Review
- Multiple myeloma with isolated central nervous system relapse after autologous stem cell transplantation: A case report and review of the literature.Frontiers in oncology · 2022Article
- Pomalidomide- and dexamethasone-based regimens in the treatment of refractory/relapsed multiple myeloma.Therapeutic advances in hematology · 2022Review
- IgD multiple myeloma with central nervous system involvement: A case report and literature review.Molecular and clinical oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central nervous system involvement is a rare complication of multiple myeloma with extremely poor prognosis as it usually fails to respond to therapy. We present 13 cases diagnosed at two centers in Budapest and review the current literature. The majority of our cases presented with high-risk features initially; two had plasma cell leukemia. Repeated genetic tests showed clonal evolution in 3 cases. Treatments varied according to the era, and efficacy was poor as generally reported in the literature. Only one patient is currently alive, with 3-month follow-up, and the patient responded to daratumumab-based treatment. Recent case reports show promising effectivity of pomalidomide and marizomib.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.