ReviewInternational journal of endocrinology2018
Nonthionamide Drugs for the Treatment of Hyperthyroidism: From Present to Future.
Review in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Article
- Iopanoic acid rapidly restores euthyroidism in refractory thyrotoxicosis pre-thyroidectomy: a retrospective study.European thyroid journal · 2026Review
- Thyroid Storm With Multiorgan Dysfunction Mimicking Sepsis: Thionamide-Sparing Bridge to Delayed Carbimazole.Cureus · 2026Article
- Case Report: Graves' disease in a toddler with maple syrup urine disease: therapeutic challenges and surgical resolution.Frontiers in pediatrics · 2026Article
- The Evaluation and Management of Methimazole-Induced Agranulocytosis in the Pediatric Patient: A Case Report and Review of the Literature.Hormone research in paediatrics · 2025Review
- Could effective iodine-131 half-life be extended by lithium carbonate in Graves' disease patients: Results from a retrospective analysis.Biomolecules & biomedicine · 2024Review
- Preoperative Preparation in Hyperthyroidism and Surgery in the Hyperthyroid State.Sisli Etfal Hastanesi tip bulteni · 2024Review
- Thyroid storm caused by metastatic papillary thyroid carcinoma tissue after total thyroidectomy: a case report.Journal of Yeungnam medical science · 2023Article
- Clinical characteristics of neutropenic patients under antithyroid drug: Twelve-year experience in a medical center.Journal of the Chinese Medical Association : JCMA · 2023Article
- Exogenous Melatonin Protects against Oxidative Damage to Membrane Lipids Caused by Some Sodium/Iodide Symporter Inhibitors in the Thyroid.Antioxidants (Basel, Switzerland) · 2023Article
- Managing hyperthyroidism patients with unconventional therapy.Archives of endocrinology and metabolism · 2022Article
- A comparison of thyroidal protection by iodine and perchlorate against radioiodine exposure in Caucasians and Japanese.Archives of toxicology · 2021Article
- Graves' disease inducing a massive cardiac tamponade.BMJ case reports · 2021Article
- Case report: a patient with thyroid storm, refractory cardiogenic shock, and cardiac arrest treated with Lugol's iodine solution and veno-arterial extra corporal membrane oxygenation support.European heart journal. Case reports · 2021Article
- Graves' disease treated by complementary medicine leading to thyroid storm: A case report.Caspian journal of internal medicine · 2021Article
- A comparison of thyroidal protection by stable iodine or perchlorate in the case of acute or prolonged radioiodine exposure.Archives of toxicology · 2020Article
- Apathetic Thyroid Storm with Cardiorespiratory Failure, Pulmonary Embolism, and Coagulopathy in a Young Male with Graves' Disease and Myopathy.Case reports in endocrinology · 2020Article
- Thyrotoxic Periodic Paralysis: A Spine Consultation.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2019Article
- Clinical Review and Update on the Management of Thyroid Storm.Missouri medicineReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hyperthyroidism is a common endocrine disease. Although thionamide antithyroid drugs are the cornerstone of hyperthyroidism treatment, some patients cannot tolerate this drug class because of its serious side effects including agranulocytosis, hepatotoxicity, and vasculitis. Therefore, nonthionamide antithyroid drugs (NTADs) still have an important role in controlling hyperthyroidism in clinical practice. Furthermore, some situations such as thyroid storm or preoperative preparation require a rapid decrease in thyroid hormone by combination treatment with multiple classes of antithyroid drugs. NTADs include iodine-containing compounds, lithium carbonate, perchlorate, glucocorticoid, and cholestyramine. In this narrative review, we summarize the mechanisms of action, indications, dosages, and side effects of currently used NTADs for the treatment of hyperthyroidism. In addition, we also describe the state-of-the-art in future drugs under development including rituximab, small-molecule ligands (SMLs), and monoclonal antibodies with a thyroid-stimulating hormone receptor (TSHR) antagonist effect.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.