Evidence map›Paper›PMID 29849617›Full record

ReviewInternational journal of endocrinology2018

The Gut Microbiome Profile in Obesity: A Systematic Review.

Olga Castaner, Albert Goday, Yong-Moon Park, Seung-Hwan Lee, Faidon Magkos, Sue-Anne Toh Ee Shiow, Helmut Schröder

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of endocrinology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05459675 (Effects of Very Low-calorie Diet Versus Bariatric Surgery on Body Composition and Gut Microbiota Pattern in Obese Patients), which is not on this map. Cited by 326 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
326citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05459675 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Effects of Very Low-calorie Diet Versus Bariatric Surgery on Body Composition and Gut Microbiota Pattern in Obese Patients

TypeinterventionalSponsorMahidol UniversityRan2022 to 2023Enrolled54ConditionsObesityArmsVery low-calorie diet, Bariatric surgery
3 · Its place in the literature

Who cites it

326 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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266 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Olga CastanerCardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain.ORCID 0000-0003-3169-997X
Albert GodayCIBER de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Santiago de Compostela, Spain.
Yong-Moon ParkEpidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA.
Seung-Hwan LeeDivision of Endocrinology & Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0002-3964-3877
Faidon MagkosDepartment of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and Clinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (ASTAR), Singapore.
Sue-Anne Toh Ee ShiowYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Helmut SchröderCardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute (IMIM), Barcelona, Spain.ORCID 0000-0003-2231-5081

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery.

Identifiers

PMID29849617
PMCPMC5933040

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.