ArticleGastroenterology research and practice2018
Serum ADAMTS-13 Levels as an Indicator of Portal Vein Thrombosis.
Article in Gastroenterology research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 19 citations in OpenAlex.
- ADAMTS13, von Willebrand Factor, Platelet Microparticles, Factor VIII, and Impact of Somatic Mutations in the Pathogenesis of Splanchnic Vein Thrombosis Associated with BCR-ABL-Negative Myeloproliferative Neoplasms.Life (Basel, Switzerland) · 2024Article
- ADAMTS-13: A Prognostic Biomarker for Portal Vein Thrombosis in Japanese Patients with Liver Cirrhosis.International journal of molecular sciences · 2024Article
- Von Willebrand factor processing in patients with advanced chronic liver disease and its relation to portal hypertension and clinical outcome.Hepatology international · 2023Article
- Narrative review of portal vein thrombosis in cirrhosis: pathophysiology, diagnosis, and management from an interventional radiology perspective.Cardiovascular diagnosis and therapy · 2022Review
- Role of von Willebrand factor in venous thromboembolic disease.JVS-vascular science · 2022Review
- Double positivity of anti-βJournal of thrombosis and thrombolysis · 2021Article
- Evaluation of coagulation parameters in dogs with gallbladder mucoceles.Journal of veterinary internal medicine · 2021Article
- Targeting von Willebrand factor in liver diseases: A novel therapeutic strategy?Journal of thrombosis and haemostasis : JTH · 2021Review
- Increased portal vein diameter is predictive of portal vein thrombosis development in patients with liver cirrhosis.Annals of translational medicine · 2021Article
- Portal vein thrombosis in cirrhosis: Why a well-known complication is still matter of debate.World journal of gastroenterology · 2019Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoagulation disorders in patients with liver cirrhosis are a common clinical problem. Cirrhosis should be considered a state of impaired blood clotting or an imbalance of the whole coagulation system. Cirrhosis-induced coagulopathy encompasses disturbances in both the procoagulant and anticoagulant systems. This mechanism may promote the development of thrombosis with portal vein thrombosis (PVT), which is considered an obstacle to orthotopic liver transplantation (OLT). We assessed serum ADAMTS-13 levels in patients with decompensated liver cirrhosis, with and without PVT. MATERIAL AND
methodsSerum ADAMTS-13 levels, age, platelet count (PLT), and INR (international normalized ratio) were evaluated in (
resultsThe mean serum ADAMTS-13 level in patients with PVT was significantly lower than that in patients without PVT (
conclusionsLow serum ADAMTS-13 levels can be a useful indicator of portal thrombosis in patients with decompensated liver cirrhosis irrespective of Child-Pugh or MELD scores. Further research is needed to determine whether ADAMTS-13 levels will find use in everyday clinical practice.
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Registered trials
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