Evidence map›Paper›PMID 29849499›Full record

ArticleMediators of inflammation

Cellular Senescence and Inflammaging in Age-Related Diseases.

Fabiola Olivieri, Francesco Prattichizzo, Johannes Grillari, Carmela R Balistreri

Registry-linked trialAbstract readEditorial
In one paragraph

Article in Mediators of inflammation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04812951 (Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age), which is not on this map. Cited by 122 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04812951 early_phase1completednot on this map

Cyclosporine 0.1% Eye Drops as Prophylactic Treatment in Post Surgical Ocular Surface System Failure Within The Age

TypeinterventionalSponsorCampus Bio-Medico UniversityRan2021 to 2022Enrolled101ConditionsOcular Surface Disease, Ocular InflammationArmsCycloSPORINE Ophthalmic 0.1% Ophthalmic Emulsion, cationorm eye drops
3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabiola OlivieriDepartment of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Italy.
Francesco PrattichizzoIRCCS MultiMedica, Milan, Italy.
Johannes GrillariUniversity of Natural Resources and Life Sciences Vienna, Vienna, Austria.
Carmela R BalistreriDepartment of Pathobiology and Medical Biotechnologies, University of Palermo, Corso Tukory 211, 90134 Palermo, Italy.ORCID 0000-0002-5393-1007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgingAnimalsCellular SenescenceHumansOxidative Stress

Identifiers

PMID29849499
PMCPMC5932453

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.