Evidence map›Paper›PMID 29849493›Full record

ArticleMediators of inflammation2018

Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice.

Vinicius F Carvalho, Emiliano O Barreto, Ana Carolina S Arantes, Magda F Serra, Tatiana Paula T Ferreira, Yago A P Jannini-Sá, Cory M Hogaboam, Marco A Martins, Patrícia M R Silva

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Vinicius F CarvalhoLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.ORCID 0000-0003-2136-8958
Emiliano O BarretoFederal University of Alagoas, 57072-970 Maceió, AL, Brazil.
Ana Carolina S ArantesLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.
Magda F SerraLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.
Tatiana Paula T FerreiraLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.
Yago A P Jannini-SáLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.
Cory M HogaboamCedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA.ORCID 0000-0003-3366-4850
Marco A MartinsLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.
Patrícia M R SilvaLaboratory of Inflammation, Oswaldo Cruz Institute, FIOCRUZ, Av. Brasil No. 4365, 21045-900 Manguinhos, RJ, Brazil.ORCID 0000-0002-6613-9000
Fundação Oswaldo Cruz · BRCedars-Sinai Medical Center · USUniversidade Federal de Alagoas · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies described that allergic diseases, including asthma, occur less often than expected in patients with type 1 diabetes. Here, we investigated the influence of diabetes on allergic airway inflammation in a model of experimental asthma in mice. Diabetes was induced by intravenous injection of alloxan into 12 h-fasted A/J mice, followed by subcutaneous sensitization with ovalbumin (OVA) and aluminum hydroxide (Al(OH)

Indexed as

AllergensAnimalsBronchoalveolar LavageChemokine CCL11Chemokine CCL3Diabetes Mellitus, ExperimentalDisease Models, AnimalInflammationInterleukin-5MaleMiceOvalbuminAllergensCcl11 protein, mouseChemokine CCL11Chemokine CCL3Interleukin-5Ovalbumin

Identifiers

PMID29849493
PMCPMC5925213
OpenAlexW2800877815

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.