Evidence map›Paper›PMID 29849492›Full record

ArticleMediators of inflammation2018

Downregulation of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia.

Yupeng Wang, Yi Sun, Xin Zhao, Renpei Yuan, Hui Jiang, Xiaoping Pu

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  6. IP3R Channels in Male Reproduction.International journal of molecular sciences · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yupeng WangNational Key Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.
Yi SunNational Key Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.ORCID 0000-0001-7043-5251
Xin ZhaoNational Key Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.
Renpei YuanDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.
Hui JiangDepartment of Urology, Peking University Third Hospital, Beijing 100191, China.ORCID 0000-0002-5417-2356
Xiaoping PuNational Key Research Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.ORCID 0000-0002-7932-5603
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthenozoospermia (AS), an important cause of male infertility, is characterized by reduced sperm motility. Among the aetiologies of AS, inflammation seems to be the main cause. DJ-1, a conserved protein product of the

Indexed as

AdultAnimalsAsthenozoospermiaBlotting, WesternHumansMaleMembrane Potential, MitochondrialMiddle AgedNADH DehydrogenaseProtein Deglycase DJ-1RatsRats, Sprague-DawleyReactive Oxygen SpeciesTestisNADH DehydrogenaseNDUFS3 protein, humanProtein Deglycase DJ-1Reactive Oxygen Species

Identifiers

PMID29849492
PMCPMC5903298
OpenAlexW2795546386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.