Evidence map›Paper›PMID 29849490›Full record

ArticleMediators of inflammation2018

The Anti-Inflammatory Effects of Shinbaro3 Is Mediated by Downregulation of the TLR4 Signalling Pathway in LPS-Stimulated RAW 264.7 Macrophages.

Hwa-Jin Chung, Wonil Koh, Won Kyung Kim, Joon-Shik Shin, Jinho Lee, Sang Kook Lee, In-Hyuk Ha

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Mediators of inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Oxidative medicine and cellular longevity · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hwa-Jin ChungJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.ORCID 0000-0002-6134-3942
Wonil KohJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.
Won Kyung KimCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
Joon-Shik ShinJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.ORCID 0000-0001-5488-3273
Jinho LeeJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.ORCID 0000-0003-0672-6892
Sang Kook LeeCollege of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul 151-742, Republic of Korea.
In-Hyuk HaJaseng Spine and Joint Research Institute, Jaseng Medical Foundation, Seoul 135-896, Republic of Korea.ORCID 0000-0002-5020-6723
Jaseng Medical Foundation · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shinbaro3, a formulation derived from the hydrolysed roots of

Indexed as

AnimalsAnti-Inflammatory AgentsHarpagophytumInterferon Regulatory Factor-3LipopolysaccharidesMiceMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NF-kappa BPlant ExtractsRAW 264.7 CellsSignal TransductionSTAT1 Transcription FactorToll-Like Receptor 4Anti-Inflammatory AgentsInterferon Regulatory Factor-3IRF3 protein, humanLipopolysaccharidesMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3NF-kappa BPlant ExtractsshinbaroSTAT1 Transcription FactorToll-Like Receptor 4

Identifiers

PMID29849490
PMCPMC5907526
OpenAlexW2795810518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.