Evidence map›Paper›PMID 29849066›Full record

ArticleScientific reports2018

Transport of Live Cells Under Sterile Conditions Using a Chemotactic Droplet.

Silvia Holler, Carlotta Porcelli, Ioannis A Ieropoulos, Martin M Hanczyc

Abstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Silvia HollerLaboratory for Artificial Biology, Centre for Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy.
Carlotta PorcelliLaboratory for Artificial Biology, Centre for Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy.
Ioannis A IeropoulosBristol BioEnergy Centre, Bristol Robotic Laboratory, Block T, UWE, Bristol, Coldharbour Lane, Bristol, BS16 1QY, UK.ORCID 0000-0002-9641-5504
Martin M HanczycLaboratory for Artificial Biology, Centre for Integrative Biology (CIBIO), University of Trento, 38123, Trento, Italy. martin.hanczyc@unitn.it.ORCID 0000-0002-5453-2139

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

1-Decanol droplets, formed in an aqueous medium containing decanoate at high pH, become chemotactic when a chemical gradient is placed in the external aqueous environment. We investigated if such droplets can be used as transporters for living cells. We developed a partially hydrophobic alginate capsule as a protective unit that can be precisely placed in a droplet and transported along chemical gradients. Once the droplets with cargo reached a defined final destination, the association of the alginate capsule and decanol droplet was disrupted and cargo deposited. Both Escherichia coli and Bacillus subtilis cells survived and proliferated after transport even though transport occurred under harsh and sterile conditions.

Indexed as

ChemotaxisBacteriaBiological TransportFatty AlcoholsHydrophobic and Hydrophilic InteractionsSaccharomyces cerevisiaeFatty Alcoholsn-decyl alcohol

Identifiers

PMID29849066
PMCPMC5976712

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.