Evidence map›Paper›PMID 29848981›Full record

ArticleMaterials (Basel, Switzerland)2018

A Single-Step Surface Modification of Electrospun Silica Nanofibers Using a Silica Binding Protein Fused with an RGD Motif for Enhanced PC12 Cell Growth and Differentiation.

Wen Shuo Chen, Ling Yu Guo, Amien Mohamed Masroujeh, Anna Morgan Augustine, Cheng Kang Tsai, Ting Yu Chin, Yui Whei Chen-Yang, Mong-Lin Yang

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Stomata biosilica andChemical science · 2025
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Wen Shuo ChenDepartment of Chemistry, Center for Nanotechnology, Center for Biomedical Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan. allanson92@yahoo.com.tw.
Ling Yu GuoDepartment of Chemistry, Center for Nanotechnology, Center for Biomedical Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan. sunny_day80917@yahoo.com.tw.
Amien Mohamed MasroujehDepartment of Science, Concordia University Saint Paul, Saint Paul, MN 55104, USA. amasroujeh@gmail.com.
Anna Morgan AugustineDepartment of Science, Concordia University Saint Paul, Saint Paul, MN 55104, USA. aaugustine@atsu.edu.
Cheng Kang TsaiDepartment of Chemistry, Center for Nanotechnology, Center for Biomedical Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan. chengkang20071994@gmail.com.
Ting Yu ChinDepartment of Bioscience Technology, Chung Yuan Christian University, Chung Li, 32023, Taiwan. tychin@cycu.edu.tw.
Yui Whei Chen-YangDepartment of Chemistry, Center for Nanotechnology, Center for Biomedical Technology, Chung Yuan Christian University, Chung Li 32023, Taiwan. yuiwhei@cycu.edu.tw.
Mong-Lin YangDepartment of Science, Concordia University Saint Paul, Saint Paul, MN 55104, USA. myang2@csp.edu.ORCID 0000-0003-4800-4206
Chung Yuan Christian University · TWConcordia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, a previously known high-affinity silica binding protein (SB) was genetically engineered to fuse with an integrin-binding peptide (RGD) to create a recombinant protein (SB-RGD). SB-RGD was successfully expressed in

Indexed as

electrospun silica nanofibersneuronal tissue engineeringRGDsilica binding protein

Identifiers

PMID29848981
PMCPMC6024934
OpenAlexW2805208068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.